公开(公告)号：US10533992B2

公开(公告)日：2020-01-14

申请号：US15559348

申请日：2015-03-19

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyoung June Kim ,  Min Sik Choi ,  Ji Yong Jung ,  Ju Yearl Park ,  Tae Ryong Lee ,  Dong Wook Shin ,  Eui Dong Son ,  Min Jung Chae

IPC: G01N33/52 ,  G01N33/53 ,  G01N33/68 ,  G01N33/50 ,  A61K8/27 ,  A61K8/29 ,  A61K33/30 ,  A61K33/00 ,  A61K33/24 ,  A61K8/37 ,  A61K8/49 ,  A61Q17/04

Abstract: Unlike a conventional method for evaluating a degree of ultraviolet protection through visual evaluation, the disclosed method for measuring a sunlight protection function can accurately and objectively measure and determine a degree of sunlight protection by measuring a change due to a material to be measured with respect to an expression amount of skin tissue antimicrobial peptides (AMPs) in skin cells, which decrease from exposure to sunlight, and/or a generation amount of S-nitrosylated protein. Additionally, the disclosed measurement method can determine whether blue/violet light of wavelengths of 400-500 nm, which induces the most skin damage among visible rays, is blocked and provide a more specified sunlight protection effect evaluation result. Moreover, by using the disclosed measurement method, a degree of sunlight protection can be indexed, and a sunlight protection composition for protecting normal skin from the blue/violet light can be provided.