公开(公告)号：US20250000892A1

公开(公告)日：2025-01-02

申请号：US18700992

申请日：2022-10-14

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Hao YAN ,  Yang XU ,  Xiaodong QIAN ,  Lu YU ,  Liangxiao CHEN

IPC: A61K31/713 ,  A61K47/68 ,  A61P35/00 ,  C07K19/00

Abstract: Described herein are RNA sequence (including siRNA, shRNA, and/or mRNA) carrier platforms for rapid and targeted delivery of siRNAs, shRNAs, and/or mRNAs into cytoplasm of tumor cells, to induce a tumor killing effect. Also described herein is are methods of treating cancer using the RNA sequence carrier platforms described herein.