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    Delivery tool for cardiac support device
    1.
    发明授权
    Delivery tool for cardiac support device 有权
    心脏支持装置的交付工具

    公开(公告)号：US07727142B2

    公开(公告)日：2010-06-01

    申请号：US11367758

    申请日：2006-03-03

    申请人： Aaron J. Hjelle ,  Paul Andrew Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    发明人： Aaron J. Hjelle ,  Paul Andrew Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    IPC分类号： A61F2/00

    CPC分类号： A61F2/2481 ,  A61B2017/00243 ,  A61B2017/22035 ,  A61B2017/2215 ,  A61F2002/2484

    摘要： A device for delivery of a cardiac support device for treating cardiac disease of a heart includes a multistage deployment mechanism and an actuating mechanism for controlling the positions of the deployment mechanism. The deployment mechanism is operable to change between a retracted state and an extended state, and includes a plurality of independent stages, including, in one embodiment, a first stage including a guide structure for location adjacent a portion of the patient's heart when in the extended state. A second stage is movably coupled to the first stage, and is guided by the guide structure between the retracted and extended states. The second stage further releasably engages and supports the cardiac support device and positions the cardiac support device at the desired implantation location, guided by the guide structure of the stage. In some embodiments, the deployment mechanism may include additional stages. The actuating mechanism drives the deployment mechanism between the retracted and extended states, and independently controls the positions of the multiple stages of the deployment mechanism.

    摘要翻译： 用于递送用于治疗心脏心脏病的心脏支持装置的装置包括多级部署机构和用于控制部署机构的位置的致动机构。 展开机构可操作以在缩回状态和延伸状态之间改变，并且包括多个独立的台阶，在一个实施例中，包括用于在延伸的患者的心脏的一部分附近定位的引导结构的第一阶段 州。 第二级可移动地联接到第一级，并且由引导结构在缩回状态和伸出状态之间引导。 第二阶段进一步可释放地接合和支撑心脏支持装置，并且将心脏支持装置定位在期望的植入位置，并由舞台的引导结构引导。 在一些实施例中，展开机构可以包括附加阶段。 致动机构在缩回状态和伸展状态之间驱动展开机构，并且独立地控制展开机构的多个阶段的位置。

    Cardiac support device delivery tool with independently movable arms
    2.
    发明授权
    Cardiac support device delivery tool with independently movable arms 有权
    心脏支持装置输送工具，具有独立的可移动臂

    公开(公告)号：US08870744B2

    公开(公告)日：2014-10-28

    申请号：US12764508

    申请日：2010-04-21

    申请人： Aaron J. Hjelle ,  Paul Andrew Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    发明人： Aaron J. Hjelle ,  Paul Andrew Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    IPC分类号： A61F2/00 ,  A61F2/24 ,  A61B17/221 ,  A61B17/22 ,  A61B17/00

    CPC分类号： A61F2/2481 ,  A61B2017/00243 ,  A61B2017/22035 ,  A61B2017/2215 ,  A61F2002/2484

    摘要： A device for delivery of a cardiac support device for treating cardiac disease of a heart includes a multistage deployment mechanism and an actuating mechanism for controlling the positions of the deployment mechanism. The deployment mechanism is operable to change between a retracted state and an extended state, and includes a plurality of independent stages, including, in one embodiment, a first stage including a guide structure for location adjacent a portion of the patient's heart when in the extended state. A second stage is movably coupled to the first stage, and is guided by the guide structure between the retracted and extended states. The second stage further releasably engages and supports the cardiac support device and positions the cardiac support device at the desired implantation location, guided by the guide structure of the stage. In some embodiments, the deployment mechanism may include additional stages. The actuating mechanism drives the deployment mechanism between the retracted and extended states, and independently controls the positions of the multiple stages of the deployment mechanism.

    摘要翻译： 用于递送用于治疗心脏心脏病的心脏支持装置的装置包括多级部署机构和用于控制部署机构的位置的致动机构。 展开机构可操作以在缩回状态和延伸状态之间改变，并且包括多个独立的台阶，在一个实施例中，包括用于在延伸的患者的心脏的一部分附近定位的引导结构的第一阶段 州。 第二级可移动地联接到第一级，并且由引导结构在缩回状态和伸出状态之间引导。 第二阶段进一步可释放地接合和支撑心脏支持装置，并且将心脏支持装置定位在期望的植入位置，并由舞台的引导结构引导。 在一些实施例中，展开机构可以包括附加阶段。 致动机构在缩回状态和伸展状态之间驱动展开机构，并且独立地控制展开机构的多个阶段的位置。

    Delivery tool for cardiac support device
    7.
    发明申请
    Delivery tool for cardiac support device 有权
    心脏支持装置的交付工具

    公开(公告)号：US20070208214A1

    公开(公告)日：2007-09-06

    申请号：US11367758

    申请日：2006-03-03

    申请人： Aaron J. Hjelle ,  Paul A. Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    发明人： Aaron J. Hjelle ,  Paul A. Pignato ,  Robert G. Walsh ,  William E. Cohn ,  Ann Margaret Thomas

    IPC分类号： A61F2/00

    CPC分类号： A61F2/2481 ,  A61B2017/00243 ,  A61B2017/22035 ,  A61B2017/2215 ,  A61F2002/2484

    摘要： A device for delivery of a cardiac support device for treating cardiac disease of a heart includes a multistage deployment mechanism and an actuating mechanism for controlling the positions of the deployment mechanism. The deployment mechanism is operable to change between a retracted state and an extended state, and includes a plurality of independent stages, including, in one embodiment, a first stage including a guide structure for location adjacent a portion of the patient's heart when in the extended state. A second stage is movably coupled to the first stage, and is guided by the guide structure between the retracted and extended states. The second stage further releasably engages and supports the cardiac support device and positions the cardiac support device at the desired implantation location, guided by the guide structure of the stage. In some embodiments, the deployment mechanism may include additional stages. The actuating mechanism drives the deployment mechanism between the retracted and extended states, and independently controls the positions of the multiple stages of the deployment mechanism.

    摘要翻译： 用于递送用于治疗心脏心脏病的心脏支持装置的装置包括多级部署机构和用于控制部署机构的位置的致动机构。 展开机构可操作以在缩回状态和延伸状态之间改变，并且包括多个独立的台阶，在一个实施例中，包括用于在延伸的患者的心脏的一部分附近定位的引导结构的第一阶段 州。 第二级可移动地联接到第一级，并且由引导结构在缩回状态和伸出状态之间引导。 第二阶段进一步可释放地接合和支撑心脏支持装置，并且将心脏支持装置定位在期望的植入位置，并由舞台的引导结构引导。 在一些实施例中，展开机构可以包括附加阶段。 致动机构在缩回状态和伸展状态之间驱动展开机构，并且独立地控制展开机构的多个阶段的位置。

    CARDIAC WALL TENSION RELIEF WITH CELL LOSS MANAGEMENT
    8.
    发明申请
    CARDIAC WALL TENSION RELIEF WITH CELL LOSS MANAGEMENT 审中-公开

    公开(公告)号：US20100261957A1

    公开(公告)日：2010-10-14

    申请号：US12824925

    申请日：2010-06-28

    申请人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    发明人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    IPC分类号： A61F2/02

    CPC分类号： A61F2/2481 ,  A61N1/326

    摘要： Methods and apparatus are disclosed for treating congestive heart failure. The method includes relieving wall stress on a diseased heart by an amount to decrease a rate of myocardial cell loss. Further, the method includes pharmacologically encouraging a myocardial cell gain. Cell gain may be encouraged by cell replication, cell recruitment or inhibition of cell death. Further embodiments of the method include a passive cardiac constraint selected to reduce wall stress on the heart. An apparatus of the present invention includes a passive cardiac constraint and a pharmacological agent to encourage cell gain.

    摘要翻译： 公开了用于治疗充血性心力衰竭的方法和装置。 该方法包括减轻患病心脏的壁应力，以减少心肌细胞损失的速率。 此外，该方法包括药理学上鼓励心肌细胞增益。 可以通过细胞复制，细胞募集或抑制细胞死亡来促进细胞增益。 该方法的另外的实施例包括被选择用于减少心脏上的壁应力的被动心脏约束。 本发明的装置包括被动心脏约束和促进细胞增益的药理学试剂。

    Cardiac wall tension relief device and method
    9.
    发明授权
    Cardiac wall tension relief device and method 有权
    心脏壁张力释放装置及方法

    公开(公告)号：US07618364B2

    公开(公告)日：2009-11-17

    申请号：US10959888

    申请日：2004-10-05

    申请人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    发明人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    IPC分类号： A61F13/00

    CPC分类号： A61N1/326 ,  A61M2205/192

    摘要： Method and apparatus are disclosed for treating congestive heart failure by administering a fibrosis-inducing agent to an epicardial surface of the heart in an amount selected to induce the formation of fibrosis on the epicardial surface. The fibrosis-inducing agent may be a drug, metal, abrasive or an electrical stimulation on the epicardial surface.

    摘要翻译： 公开了通过以选择用于在心外膜表面上诱导纤维化形成的量向心外膜表面施用纤维化诱导剂来治疗充血性心力衰竭的方法和装置。 纤维化诱导剂可以是在心外膜表面上的药物，金属，研磨剂或电刺激。

    CARDIAC WALL TENSION RELIEF WITH CELL LOSS MANAGEMENT
    10.
    发明申请
    CARDIAC WALL TENSION RELIEF WITH CELL LOSS MANAGEMENT 审中-公开

    公开(公告)号：US20080125622A1

    公开(公告)日：2008-05-29

    申请号：US12027093

    申请日：2008-02-06

    申请人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    发明人： Robert G. Walsh ,  Paul Andrew Pignato ,  Ann Margaret Thomas

    IPC分类号： A61F2/02

    CPC分类号： A61F2/2481 ,  A61N1/326

    摘要： Methods and apparatus are disclosed for treating congestive heart failure. The method includes relieving wall stress on a diseased heart by an amount to decrease a rate of myocardial cell loss. Further, the method includes pharmacologically encouraging a myocardial cell gain. Cell gain may be encouraged by cell replication, cell recruitment or inhibition of cell death. Further embodiments of the method include a passive cardiac constraint selected to reduce wall stress on the heart. An apparatus of the present invention includes a passive cardiac constraint and a pharmacological agent to encourage cell gain.

    摘要翻译： 公开了用于治疗充血性心力衰竭的方法和装置。 该方法包括减轻患病心脏的壁应力，以减少心肌细胞损失的速率。 此外，该方法包括药理学上鼓励心肌细胞增益。 可以通过细胞复制，细胞募集或抑制细胞死亡来促进细胞增益。 该方法的另外的实施例包括被选择用于减少心脏上的壁应力的被动心脏约束。 本发明的装置包括被动心脏约束和促进细胞增益的药理学试剂。