公开(公告)号：US20150132249A1

公开(公告)日：2015-05-14

申请号：US14590590

申请日：2015-01-06

Applicant: Abbott Cardiovascular Systems, Inc.

Inventor： Gina Zhang ,  Jessica Renee DesNoyer ,  Gordon Stewart ,  Maricela Kezis ,  Syed Faiyaz Ahmed Hossainy

IPC: A61K47/48 ,  C08G69/44 ,  A61K31/436

CPC classification number: A61K31/436 ,  A61K9/0019 ,  A61K47/595 ,  A61L24/001 ,  A61L24/046 ,  A61L2430/36 ,  C08G69/44 ,  Y10S977/906 ,  C08L77/12

Abstract: A composition including a solution suitable for introduction into a blood vessel comprising particles including a treatment agent and a tunable stimuli-responsive polymer. A method including introducing a delivery device into a blood vessel; and introducing a solution into the blood vessel, the solution including particles comprising a treatment agent and a tunable stimuli-responsive polymer. A method including combining a treatment agent and a tunable stimuli-responsive polymer; and forming particles of the combination suitable for delivery through a blood vessel.

Abstract translation: 一种包含适于引入血管的溶液的组合物，其包含包含处理剂和可调节刺激响应性聚合物的颗粒。 一种包括将输送装置引入血管的方法; 并且将溶液引入血管中，所述溶液包括包含处理剂和可调节刺激响应性聚合物的颗粒。 一种包括处理剂和可调谐刺激响应性聚合物的组合的方法; 以及形成适于通过血管输送的组合颗粒。

公开(公告)号：US09216027B2

公开(公告)日：2015-12-22

申请号：US14053456

申请日：2013-10-14

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Paul M. Consigny ,  William E. Webler ,  Gustavo D. Cipolla ,  Gordon Stewart ,  Benny Serna ,  Daniel L. Cox

IPC: A61M25/10 ,  A61B17/22 ,  A61M25/00

CPC classification number: A61M25/104 ,  A61B17/22 ,  A61B2017/22042 ,  A61B2017/22051 ,  A61B2017/22084 ,  A61M25/10 ,  A61M2025/0057 ,  A61M2025/105 ,  A61M2025/1081

Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.

公开(公告)号：US20140046253A1

公开(公告)日：2014-02-13

申请号：US14053456

申请日：2013-10-14

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Paul M. Consigny ,  William E. Webler ,  Gustavo D. Cipolla ,  Gordon Stewart ,  Benny Serna ,  Daniel L. Cox

IPC: A61M25/10

CPC classification number: A61M25/104 ,  A61B17/22 ,  A61B2017/22042 ,  A61B2017/22051 ,  A61B2017/22084 ,  A61M25/10 ,  A61M2025/0057 ,  A61M2025/105 ,  A61M2025/1081

Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.

Abstract translation: 公开了用于在处理部位洗脱试剂的系统，装置和方法。 这些装置包括可扩张框架和至少一个膜片。 膜可以携带一种药剂在治疗部位洗脱。 在给药期间，膜可允许血液在治疗部位流动。