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公开(公告)号：US12121630B2
公开(公告)日：2024-10-22
申请号：US17271817
申请日：2019-09-03
CPC分类号： A61L27/50 , A61L24/001 , A61L24/104 , A61L27/222 , A61L2400/06 , A61L2430/16 , B29C35/0805 , B29K2089/00 , B29K2907/00 , B29L2031/753
摘要： The present invention discloses compositions and methods for repair and reconstruction of defects and injuries to soft tissues. Some aspects of the disclosure provide methods for corneal reconstruction by applying an engineered bioadhesive, glycidyl methacrylate-substituted gelatin and a visible light activated photoinitiator in presence of visible light to the corneal defect.
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2.发明公开公开(公告)号：US20240327335A1
公开(公告)日：2024-10-03
申请号：US18027511
申请日：2022-11-02
发明人： Hongtao Sun , Xin Li , Jinpeng Xiao , Peng Sun , Haibo Che
IPC分类号： C07C233/76 , A61L24/00 , A61L24/04
CPC分类号： C07C233/76 , A61L24/001 , A61L24/043
摘要： Disclosed are an amide compound having iodoaryl or iodoheteroaryl, a preparation method therefor and a use thereof. The amide compound having iodoaryl or iodoheteroaryl can be used to prepare an X-ray imaging embolic material with improved imaging modification efficiency, thus increasing the iodine content of the X-ray imaging embolic material.
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公开(公告)号：US20240316243A1
公开(公告)日：2024-09-26
申请号：US18290042
申请日：2022-05-11
CPC分类号： A61L24/046 , A61B17/0057 , A61L24/001 , A61L2400/06 , A61L2430/36
摘要： This disclosure relates to devices, method, and material compositions. Specifically, the present invention related to a delivery device to deliver a material composition that seals a tract, for example during a percutaneous intervention.
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公开(公告)号：US11992575B2
公开(公告)日：2024-05-28
申请号：US16750635
申请日：2020-01-23
申请人： MicroVention, Inc.
发明人： Gregory M. Cruise , Xinping Wu , Matthew J. Fitz , Yue Wu
IPC分类号： A61L24/00
CPC分类号： A61L24/0005 , A61L24/001 , A61L24/0015 , A61L2300/428 , A61L2300/44 , A61L2400/12 , A61L2430/36
摘要： Liquid embolic preparations and medical treatment methods of using those preparations are described. In some embodiments, the preparations or solutions can transition from a liquid to a solid for use in the embolization. The preparations can include biocompatible polymers with covalently bound radioactive iodine isotopes.
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公开(公告)号：US11986571B2
公开(公告)日：2024-05-21
申请号：US17291075
申请日：2020-04-01
CPC分类号： A61L24/001 , A61L24/0015 , A61L24/06 , A61L2300/106 , A61L2300/418 , A61L2430/36
摘要： The invention relates to radiopaque liquid embolic composition comprising tetra iodo compound, 4,4-bis (4-hydroxy-3,5 diiodo phenyl) valeric acid (IBHV) of Formula I, covalently linked to ethylene vinyl alcohol copolymer (EVOH) and dissolved in a water miscible organic liquid.
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6.发明授权公开(公告)号：US11931227B2
公开(公告)日：2024-03-19
申请号：US15581876
申请日：2017-04-28
CPC分类号： A61F13/04 , A61F13/00063 , A61F13/023 , A61F13/0253 , A61L15/225 , A61L15/58 , A61L24/001 , A61L26/0061 , A61L2300/418 , A61L2400/04 , A61L2400/06
摘要： The present invention relates to a long-lasting medical product for protecting or treating a lesion in the gastrointestinal tract. The medical product includes a protective covering, wherein the medical product upon application at and about the site of the lesion adheres to the gastrointestinal tissue and is capable of remaining at and about the site of the lesion for a time sufficient to allow the lesion to heal or be treated.
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公开(公告)号：US11904068B2
公开(公告)日：2024-02-20
申请号：US17651509
申请日：2022-02-17
IPC分类号： A61B17/34 , A61F6/22 , A61L24/00 , A61L24/06 , A61L27/52 , A61L27/54 , A61K49/22 , A61B8/08 , A61B17/12 , A61B17/42
CPC分类号： A61L24/06 , A61B8/085 , A61B8/0833 , A61B8/0841 , A61B17/12 , A61B17/12022 , A61B17/12186 , A61B17/3403 , A61F6/22 , A61K49/223 , A61K49/226 , A61L24/001 , A61L24/0015 , A61L24/0031 , A61L24/0036 , A61L27/52 , A61L27/54 , A61B8/0891 , A61B8/481 , A61B8/488 , A61B17/42 , A61B2017/3413 , A61L2300/626 , A61L2400/06 , A61L2430/36
摘要： Disclosed are methods of delivering an agent to the lumen of the vas deferens under guidance of ultrasound imaging. The methods include vas-occlusive contraception in which the vas deferens is non-surgically isolated and an occlusive substance is percutaneously administered into the lumen of the vas deferens under ultrasound. Also disclosed are methods of reversal of vas-occlusive contraception and methods of delivering an agent to the lumen of the vas deferens. Also disclosed are compositions for use in the methods of the invention.
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公开(公告)号：US20240001134A1
公开(公告)日：2024-01-04
申请号：US18216258
申请日：2023-06-29
申请人： Novocure GmbH
CPC分类号： A61N1/40 , H01B1/24 , A61L24/02 , A61L24/001 , A61L24/0078 , A61K9/0009 , A61L2400/00
摘要： An adhesive layer for use in a transducer apparatus, the adhesive layer extending in an x-y plane and having an adhesive layer outer edge, the adhesive layer including: an adhesive matrix material; a plurality of electrically conductive particles embedded at least partially within the adhesive matrix material forming a conductive adhesive region of the adhesive layer; and at least one non-conductive edge portion comprising an adhesive devoid of electrically conductive particles, the at least one non-conductive edge portion being electrically non-conductive; wherein, when viewed in a direction perpendicular to the x-y plane, a first non-conductive edge portion is located adjacent to and extends along an outer edge of the conductive adhesive region and forms at least a portion of an outer perimeter of the adhesive layer.
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公开(公告)号：US11863305B2
公开(公告)日：2024-01-02
申请号：US17751864
申请日：2022-05-24
发明人： Paul Snow
IPC分类号： H04L9/06 , H04L9/32 , G06F21/60 , G06F16/23 , H04L9/08 , H04L9/00 , G06F16/2458 , A61B1/018 , A61B1/273 , A61J1/05 , A61J1/06 , A61K49/00 , A61L24/00 , A61L24/04 , A61L31/06 , A61M5/00 , A61M5/178 , A61M5/32 , A61M39/10 , G06F12/0815
CPC分类号： H04L9/0637 , A61B1/018 , A61B1/273 , A61J1/05 , A61J1/06 , A61K49/006 , A61L24/001 , A61L24/046 , A61L31/06 , A61M5/007 , A61M5/178 , A61M5/329 , A61M39/10 , G06F12/0815 , G06F16/2379 , G06F16/2465 , G06F21/602 , H04L9/0643 , H04L9/0869 , H04L9/3218 , H04L9/3236 , H04L9/3239 , A61L2300/442 , A61L2400/06 , G06F2212/1016 , G06F2216/03 , H04L9/50
摘要： Blockchain environments may mix-and-match different encryption, difficulty, and/or proof-of-work schemes when mining blockchain transactions. Each encryption, difficulty, and/or proof-of-work scheme may be separate, stand-alone programs, files, or third-party services. Blockchain miners may be agnostic to a particular coin's or network's encryption, difficulty, and/or proof-of-work schemes, thus allowing any blockchain miner to process or mine data in multiple blockchains. GPUs, ASICs, and other specialized processing hardware components may be deterred by forcing cache misses, cache latencies, and processor stalls. Hashing, difficulty, and/or proof-of-work schemes require less programming code, consume less storage space/usage in bytes, and execute faster. Blockchain mining schemes may further randomize byte or memory block access, further improve cryptographic security.
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公开(公告)号：US20230279172A1
公开(公告)日：2023-09-07
申请号：US18317747
申请日：2023-05-15
发明人： Andrew Lennard Lewis , Hugh Britton , Yiqing Tang , Jonathan Vince , Koorosh Ashrafi , Damien Guégan
CPC分类号： C08F261/04 , A61K9/0024 , A61K9/1635 , A61K49/0442 , A61L24/001 , A61L24/0015 , A61L24/046 , C08G67/00 , A61L2400/06 , A61L2430/36
摘要： This invention relates to radiopaque polymers and to their use, particularly in the manufacture of medical devices and in methods of medical treatment, including therapeutic embolization. In particular embodiments the present disclosure relates to a hydrophilic polymer comprising pendent groups which a phenyl ring is substituted with one or more iodine groups and one or more non-iodine groups as described in more detail herein.
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