公开(公告)号：US20250027009A1

公开(公告)日：2025-01-23

申请号：US18714323

申请日：2022-11-22

Applicant: BASF SE

Inventor： Ben Chuan Zhu ,  Fang Qin Lin ,  Yan Xiao ,  Shou Dao Zhang ,  Claudia Brunn ,  Detlev Stanislowski

IPC: C11C1/00 ,  A61K8/46 ,  A61Q19/00

Abstract: The present invention is related to a method for purifying crude α-sulfo fatty acid salt obtained by the reaction of fatty acid and sulfur oxides, comprising the following steps: a) diluting the crude α-sulfo fatty acid in a solvent and adjusting the ph from 2 to 4; b) heating up the slurry of a-sulfo fatty acid salt obtained in the step a) until being fully solubilized: c) cooling down the solution of α-sulfo fatty acid salt obtained in the step b) to room temperature gradually to obtain the crystals; d) filtering the crystal obtained in the step c) to remove the motherinsing the filter cake at least twice with acid aqueous solution to obtain the purified α-sulfo fatty acid salt.