公开(公告)号：US20220326240A1

公开(公告)日：2022-10-13

申请号：US17715988

申请日：2022-04-08

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： RAVI KAUL ,  SHUXIA ZHOU ,  ROGER P. WALKER

IPC: G01N33/569 ,  G01N33/573 ,  G01N33/62 ,  G01N33/533 ,  G01N1/40

Abstract: The present disclosure relates to the development of novel immunoassays for the detection of SARS-CoV-2 or secreted spike protein (or fragments thereof) in saliva, nasal mucosal sample, throat samples, or nasopharyngeal samples.

公开(公告)号：US20220018838A1

公开(公告)日：2022-01-20

申请号：US17379193

申请日：2021-07-19

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： QIAN GAO ,  RAVI KAUL ,  SHUXIA ZHOU ,  ROGER P. WALKER

IPC: G01N33/569 ,  G01N21/64

Abstract: The present invention relates to the development of novel immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples. Novel multiplex and singleplex immunoassays for the detection of neutralizing antibodies and/or high avidity neutralizing antibodies to SARS-CoV-2 spike protein variants or fragments thereof and, optionally, one or more cytokine in patient samples are also provided.