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公开(公告)号：US20250027066A1
公开(公告)日：2025-01-23
申请号：US18708333
申请日：2022-11-09
Applicant: BIONTECH SE
Inventor： Ugur Sahin , Andreas Henning , Stephanie Erbar , Stefan Albrecht Schille , Anna Spier , Lorenzo Corsini , Zehra Visram
Abstract: The invention provides agents and methods for treating bacterial infections using RNA. The RNA encoding peptidoglycan hydrolases. e.g., endolysins, is formulated and administered in a way that peptidoglycan hydrolase proteins. e.g., endolysin proteins, can be produced and secreted by cells of a subject to combat bacterial infections.
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