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公开(公告)号：US20190099506A1
公开(公告)日：2019-04-04
申请号：US16148604
申请日：2018-10-01
Applicant: Bristol-Myers Squibb Company
Inventor： Michael J. Smith , Haiying Tang , Paul E. Morin , Harold J. Malone
Abstract: Deuterated polymer-biomolecule conjugates and the synthesis and use of deuterated polymer-biomolecule conjugates for detecting the location of specific molecules, e.g., cell surface molecules, in a subject, and for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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公开(公告)号：US20210060184A1
公开(公告)日：2021-03-04
申请号：US17093941
申请日：2020-11-10
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Michael J. SMITH , Haiying Tang , Paul E Morin , Harold J. Malone , Luciano MUELLER
Abstract: Deuterated polymer-biomolecule conjugates and the synthesis and use of deuterated polymer-biomolecule conjugates for detecting the location of specific molecules, e.g., cell surface molecules, in a subject, and for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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公开(公告)号：US11623013B2
公开(公告)日：2023-04-11
申请号：US17093941
申请日：2020-11-10
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Michael J. Smith , Haiying Tang , Paul E. Morin , Harold J. Malone , Luciano Mueller
Abstract: Deuterated polymer-biomolecule conjugates and the synthesis and use of deuterated polymer-biomolecule conjugates for detecting the location of specific molecules, e.g., cell surface molecules, in a subject, and for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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