公开(公告)号：US11685787B2

公开(公告)日：2023-06-27

申请号：US16612956

申请日：2018-05-15

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Suba Krishnan ,  Penny E. Phillips ,  Zheng Yang ,  Haiqing Wang

IPC: A61P35/00 ,  C07K16/28 ,  A61K39/00

CPC classification number: C07K16/2878 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  A61K2039/507 ,  A61K2039/545 ,  C07K2317/75 ,  C07K2317/76

Abstract: Provided herein are methods for treating cancer, comprising administering to a subject having cancer a therapeutically effective amount of an anti-GITR antibody alone or together with an anti-PD-1 or anti-PD-L1 antibody.

公开(公告)号：US11351163B2

公开(公告)日：2022-06-07

申请号：US16649277

申请日：2018-09-28

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Paul Andrew Basciano ,  Justine Kamilah Walker ,  Penny E. Phillips ,  Li Zhu ,  Steven H. Bernstein ,  James Cassidy ,  Katy Lynn Simonsen ,  Alexander Azrilevich ,  Shivani Srivastava

IPC: A61K31/47 ,  A61P35/00 ,  A61P35/04 ,  A61K9/00 ,  A61K45/06 ,  C07K16/28

Abstract: The disclosure is directed to methods of treating cancer in subjects with a combination of a monoclonal antibody and (R)-N-(4-chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide, or a salt thereof.