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1.发明申请Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds and/or substituted 2-heteroaryl-aminoacetic acid compounds 失效含有取代的2-芳基 - 氨基乙酸化合物和/或取代的2-杂芳基 - 氨基乙酸化合物的药物制剂公开(公告)号：US20060035959A1
公开(公告)日：2006-02-16
申请号：US11202037
申请日：2005-08-12
IPC分类号： A61K31/382 , A61K31/381 , A61K31/343 , A61K31/198
CPC分类号： A61K31/343 , A61K31/198 , A61K31/381 , A61K31/385 , A61K31/39
摘要： Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds and/or substituted 2-heteroaryl-aminoacetic acid compounds corresponding to formula I, as well as to their use in the production of drugs and in related methods of treating or inhibiting pain and neurodegenerative disease.
摘要翻译： 含有对应于式I的取代的2-芳基 - 氨基乙酸化合物和/或取代的2-杂芳基 - 氨基乙酸化合物的药物制剂以及它们在制备药物中的用途以及用于治疗或抑制疼痛和神经变性疾病的相关方法 。
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2.发明申请Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds 失效含有取代的2个杂芳基氨基乙酸化合物的药物制剂公开(公告)号：US20060025473A1
公开(公告)日：2006-02-02
申请号：US11202074
申请日：2005-08-12
IPC分类号： A61K31/381 , A61K31/343
CPC分类号： A61K31/381 , A61K31/343
摘要： Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds corresponding to formula I and their use in the production of drugs and in related methods of treatment or inhibition of certain conditions or diseases.
摘要翻译： 含有对应于式I的取代的2-芳基 - 氨基乙酸化合物的药物制剂及其在制备药物中的用途以及治疗或抑制某些病症或疾病的相关方法。
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3.发明授权Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds and/or substituted 2-heteroaryl-aminoacetic acid compounds 失效含有取代的2-芳基 - 氨基乙酸化合物和/或取代的2-杂芳基 - 氨基乙酸化合物的药物制剂公开(公告)号：US07432296B2
公开(公告)日：2008-10-07
申请号：US11202037
申请日：2005-08-12
CPC分类号： A61K31/343 , A61K31/198 , A61K31/381 , A61K31/385 , A61K31/39
摘要： Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds and/or substituted 2-heteroaryl-aminoacetic acid compounds corresponding to formula I, as well as to their use in the production of drugs and in related methods of treating or inhibiting pain and neurodegenerative disease.
摘要翻译： 含有对应于式I的取代的2-芳基 - 氨基乙酸化合物和/或取代的2-杂芳基 - 氨基乙酸化合物的药物制剂以及它们在制备药物中的用途以及用于治疗或抑制疼痛和神经变性疾病的相关方法 。
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4.发明授权Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds 失效含有取代的2个杂芳基氨基乙酸化合物的药物制剂公开(公告)号：US07754754B2
公开(公告)日：2010-07-13
申请号：US11202074
申请日：2005-08-12
IPC分类号： A61K31/405 , A61K9/20 , A61K9/14 , A61K31/38 , A01N43/12
CPC分类号： A61K31/381 , A61K31/343
摘要： Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds corresponding to formula I and their use in the production of drugs and in related methods of treatment or inhibition of certain conditions or diseases.
摘要翻译： 含有对应于式I的取代的2-芳基 - 氨基乙酸化合物的药物制剂及其在制备药物中的用途以及治疗或抑制某些病症或疾病的相关方法。
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5.发明授权Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines for use in treating pain, depression and/or anxiety 失效饱和和不饱和的3-吡啶基 - 苯并环烷基甲基胺，用于治疗疼痛，抑郁和/或焦虑公开(公告)号：US08278338B2
公开(公告)日：2012-10-02
申请号：US11643792
申请日：2006-12-22
申请人： Bernd Sundermann , Hagen-Heinrich Hennies , Klaus Schiene , Petra Bloms-Funke , Werner Englberger , Sven Frormann , Derek Saunders
发明人： Bernd Sundermann , Hagen-Heinrich Hennies , Klaus Schiene , Petra Bloms-Funke , Werner Englberger , Sven Frormann , Derek Saunders
IPC分类号： A61K31/4402 , C07D213/24
CPC分类号： C07D417/06 , C07D213/38 , C07D413/06
摘要： Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines=compounds corresponding to formula (I), wherein the various substituents have the meaning provided in the description, and pharmaceutical formulations containing these compounds and methods for producing these compounds and related pharmaceutical formulation, and to methods for treating or inhibiting pain, depression and/or anxiety states.
摘要翻译： 饱和和不饱和的3-吡啶基 - 苯并环烷基甲基胺=对应于式（I）的化合物，其中各种取代基具有说明书中提供的含义，以及含有这些化合物的药物制剂以及用于制备这些化合物和相关药物制剂的方法，以及 用于治疗或抑制疼痛，抑郁和/或焦虑状态的方法。
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6.发明授权Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants 有权饱和和不饱和的杂芳基环烷基甲基胺作为抗抑郁剂公开(公告)号：US07384961B2
公开(公告)日：2008-06-10
申请号：US11155766
申请日：2005-06-20
申请人： Petra Bloms-Funke , Claudia Puetz , Ivars Graudums , Achim Kless , Carsten Griebel , Hagen-Heinrich Hennies , Dagmar Kaulartz , Sabine Reinardy , Derek Saunders , Klaus Schiene , Bernd Sundermann , Werner Englberger , Oswald Zimmer
发明人： Petra Bloms-Funke , Claudia Puetz , Ivars Graudums , Achim Kless , Carsten Griebel , Hagen-Heinrich Hennies , Dagmar Kaulartz , Sabine Reinardy , Derek Saunders , Klaus Schiene , Bernd Sundermann , Werner Englberger , Oswald Zimmer
IPC分类号： A61K31/44 , A61K31/13 , C07D401/00
CPC分类号： C07D405/04 , C07D213/38 , C07D213/61 , C07D213/65
摘要： Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
摘要翻译： 对应于式I的饱和和不饱和的杂芳基环烷基甲基 - 胺化合物，其制备方法，包含这些化合物的药物制剂以及使用饱和和不饱和的杂芳基环烷基甲基胺用于制备药物制剂。 还公开了药物制剂和治疗或预防某些病症，特别是抑郁症和/或疼痛的相关方法。
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7.发明申请Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines for use in treating pain, depression and/or anxiety 失效饱和和不饱和的3-吡啶基 - 苯并环烷基甲基胺，用于治疗疼痛，抑郁和/或焦虑公开(公告)号：US20070203192A1
公开(公告)日：2007-08-30
申请号：US11643792
申请日：2006-12-22
申请人： Bernd Sundermann , Hagen-Heinrich Hennies , Klaus Schiene , Petra Bloms-Funke , Werner Englberger , Sven Frormann , Derek Saunders
发明人： Bernd Sundermann , Hagen-Heinrich Hennies , Klaus Schiene , Petra Bloms-Funke , Werner Englberger , Sven Frormann , Derek Saunders
IPC分类号： A61K31/4433 , A61K31/4436 , A61K31/44 , C07D409/02 , C07D405/02
CPC分类号： C07D417/06 , C07D213/38 , C07D413/06
摘要： Saturated and unsaturated 3-pyridyl-benzocycloalkylmethyl-amines=compounds corresponding to formula (I), wherein the various substituents have the meaning provided in the description, and pharmaceutical formulations containing these compounds and methods for producing these compounds and related pharmaceutical formulation, and to methods for treating or inhibiting pain, depression and/or anxiety states.
摘要翻译： 饱和和不饱和的3-吡啶基 - 苯并环烷基甲基胺=对应于式（I）的化合物，其中各种取代基具有说明书中提供的含义，以及含有这些化合物的药物制剂以及用于制备这些化合物和相关药物制剂的方法，以及 用于治疗或抑制疼痛，抑郁和/或焦虑状态的方法。
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8.发明申请Saturated and unsaturated heteroarylcycloalkylmethyl amines as anti-depressants 有权饱和和不饱和的杂芳基环烷基甲基胺作为抗抑郁剂公开(公告)号：US20060025456A1
公开(公告)日：2006-02-02
申请号：US11155766
申请日：2005-06-20
申请人： Petra Bloms-Funke , Claudia Puetz , Ivars Graudums , Achim Kless , Carsten Griebel , Hagen-Heinrich Hennies , Dagmar Kaulartz , Sabine Reinardy , Derek Saunders , Klaus Schiene , Bernd Sundermann , Werner Englberger , Oswald Zimmer
发明人： Petra Bloms-Funke , Claudia Puetz , Ivars Graudums , Achim Kless , Carsten Griebel , Hagen-Heinrich Hennies , Dagmar Kaulartz , Sabine Reinardy , Derek Saunders , Klaus Schiene , Bernd Sundermann , Werner Englberger , Oswald Zimmer
IPC分类号： A61K31/44 , C07D213/26
CPC分类号： C07D405/04 , C07D213/38 , C07D213/61 , C07D213/65
摘要： Saturated and unsaturated heteroarylcycloalkylmethyl-amine compounds corresponding to formula I, processes for their preparation, pharmaceutical formulations comprising these compounds and the use of saturated and unsaturated heteroarylcycloalkylmethyl-amines for the preparation of pharmaceutical formulations. pharmaceutical formulations and related methods of treatment or prophylaxis of certain condition, especially depression and/or pain, are also disclosed.
摘要翻译： 对应于式I的饱和和不饱和的杂芳基环烷基甲基 - 胺化合物，其制备方法，包含这些化合物的药物制剂以及使用饱和和不饱和的杂芳基环烷基甲基胺用于制备药物制剂。 还公开了药物制剂和治疗或预防某些病症，特别是抑郁症和/或疼痛的相关方法。
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9.发明申请Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions 有权香草素受体配体，含有它们的药物组合物及其制备方法及其用途，用于治疗疼痛和其他病症公开(公告)号：US20110184020A1
公开(公告)日：2011-07-28
申请号：US13077452
申请日：2011-03-31
申请人： Robert FRANK , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jeewoo Lee
发明人： Robert FRANK , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jeewoo Lee
IPC分类号： A61K31/4545 , A61K31/44 , C07D401/04 , C07D213/70 , C07D213/64 , A61P9/12 , A61P29/00 , A61P25/06 , A61P25/24 , A61P25/28 , A61P25/08 , A61P25/00 , A61P25/16 , A61P11/00 , A61P1/04 , A61P1/00 , A61P1/12 , A61P19/02 , A61P25/32 , A61P9/00 , A61P17/02 , A61P11/06 , A61P3/04
CPC分类号： C07D213/74 , C07D213/64 , C07D213/70
摘要： Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
摘要翻译： 对应于式I的香草酸受体配体化合物：制备这种化合物的方法，含有它们的药物组合物，以及这些化合物用于治疗疼痛和各种其它香草素受体介导的病症的用途。
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10.发明申请Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions 失效香草素受体配体，含有它们的药物组合物及其制备方法及其用途，用于治疗疼痛和其他病症公开(公告)号：US20080262039A1
公开(公告)日：2008-10-23
申请号：US12103198
申请日：2008-04-15
申请人： Robert FRANK , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jewoo Lee
发明人： Robert FRANK , Gregor Bahrenberg , Thomas Christoph , Klaus Schiene , Jean De Vry , Derek Saunders , Michael Przewosny , Bernd Sundermann , Jewoo Lee
IPC分类号： C07D401/04 , C07D211/00 , A61K31/4545 , A61K31/44 , A61P11/00 , A61P1/00 , A61P17/06 , A61P9/00 , A61P31/12 , A61P25/30
CPC分类号： C07D213/74 , C07D213/64 , C07D213/70
摘要： Vanilloid receptor ligand compounds corresponding to formula I: a process for producing such compounds, pharmaceutical compositions containing them, and the use of such compounds to treat pain and various other vanilloid receptor mediated conditions.
摘要翻译： 对应于式I的香草酸受体配体化合物：制备这种化合物的方法，含有它们的药物组合物，以及这些化合物用于治疗疼痛和各种其它香草素受体介导的病症的用途。
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