公开(公告)号：US20120122893A1

公开(公告)日：2012-05-17

申请号：US13294624

申请日：2011-11-11

Applicant: Joseph Anand REDDY ,  Christopher Paul LEAMON ,  Binh NGUYEN

Inventor： Joseph Anand REDDY ,  Christopher Paul LEAMON ,  Binh NGUYEN

IPC: A61K31/519 ,  A61P35/00

CPC classification number: A61K38/08 ,  A61K31/282 ,  A61K31/337 ,  A61K31/4745 ,  A61K31/517 ,  A61K31/519 ,  A61K31/704 ,  A61K31/7068 ,  A61K33/24 ,  A61K39/3955 ,  A61K45/06 ,  A61K2300/00

Abstract: Described are methods and compositions for treating epithelial tumors with a folate-vinca conjugate in combination with at least one other chemotherapeutic agent in which the tumors include ovarian, endometrial or non-small cell lung cancer tumors, including platinum-resistant ovarian tumors and platinum-sensitive ovarian tumors.

Abstract translation: 描述了用叶酸 - 长春花碱缀合物与至少一种其他化学治疗剂联合治疗上皮肿瘤的方法和组合物，其中肿瘤包括卵巢，子宫内膜或非小细胞肺癌肿瘤，包括耐铂性卵巢肿瘤和铂 - 敏感的卵巢肿瘤。

公开(公告)号：US20080034552A1

公开(公告)日：2008-02-14

申请号：US11675164

申请日：2007-02-15

Applicant: Binh NGUYEN

Inventor： Binh NGUYEN

IPC: E05D11/06

CPC classification number: E05D3/145 ,  E05D11/06 ,  E05Y2201/224 ,  E05Y2201/696 ,  E05Y2600/20 ,  E05Y2900/536 ,  E05Y2900/548 ,  Y10T16/551 ,  Y10T16/5513

Abstract: A hinge for use in a motor vehicle, including first and second members pivotably coupled to each other. First and second position retainers are coupled between the first member and the second member to releasably secure the second member in a first holding position relative to the first member. The first position retainer has a first holding portion and the second position retainer has a second holding portion such that one of the first and second position retainers is structured and arranged to move relative to the other of the first and second position retainers such that the first and second holding portions move into and out from a first holding position. The first and second holding portions are structured and arranged to be releasably secured to each other in the first holding position.

Abstract translation: 一种用于机动车辆的铰链，包括彼此可枢转地联接的第一和第二构件。 第一和第二位置保持器联接在第一构件和第二构件之间，以将第二构件可释放地固定在相对于第一构件的第一保持位置。 第一位置保持器具有第一保持部分，并且第二位置保持器具有第二保持部分，使得第一和第二位置保持器中的一个被构造和布置成相对于第一和第二位置保持器中的另一个移动，使得第一位置保持器 并且第二保持部分从第一保持位置移入和移出。 第一和第二保持部分构造和布置成在第一保持位置可释放地彼此固定。