-
公开(公告)号:US20240185950A1
公开(公告)日:2024-06-06
申请号:US18538076
申请日:2023-12-13
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Michael Samuels , Jeffrey Olson , Darren R. Link
Abstract: In certain aspects, methods of the invention involve performing modification state specific enzymatic reaction of nucleic acid in a sample, determining a value associated with efficiency of the modification state specific enzymatic reaction based on a control, determining an amount of target nucleic acid in the sample, and normalizing the amount of target nucleic acid based on the efficiency value. Based on the normalized amount of target nucleic acid, the method further includes determining whether the normalized amount of target nucleic acid is indicative of a condition.
-
公开(公告)号:US11901041B2
公开(公告)日:2024-02-13
申请号:US14505974
申请日:2014-10-03
Applicant: Bio-Rad Laboratories, Inc.
Inventor: Michael Samuels , Jeffrey Olson , Darren R. Link
Abstract: In certain aspects, methods of the invention involve performing modification state specific enzymatic reaction of nucleic acid in a sample, determining a value associated with efficiency of the modification state specific enzymatic reaction based on a control, determining an amount of target nucleic acid in the sample, and normalizing the amount of target nucleic acid based on the efficiency value. Based on the normalized amount of target nucleic acid, the method further includes determining whether the normalized amount of target nucleic acid is indicative of a condition.
-