公开(公告)号：US11833507B2

公开(公告)日：2023-12-05

申请号：US17590543

申请日：2022-02-01

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan Handique ,  Swati Ranade ,  Vishal Sharma ,  Austin Payne ,  Sam Tuck

IPC: B01L3/00 ,  C12N13/00

CPC classification number: B01L3/502 ,  C12N13/00 ,  B01L2200/026 ,  B01L2300/0893 ,  B01L2400/043

Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).

公开(公告)号：US20220152606A1

公开(公告)日：2022-05-19

申请号：US17590543

申请日：2022-02-01

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan Handique ,  Swati Ranade ,  Vishal Sharma ,  Austin Payne ,  Sam Tuck

IPC: B01L3/00 ,  C12N13/00

Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).

公开(公告)号：US11273439B2

公开(公告)日：2022-03-15

申请号：US16906337

申请日：2020-06-19

Applicant: Bio-Rad Laboratories, Inc

Inventor： Kalyan Handique ,  Swati Ranade ,  Vishal Sharma ,  Austin Payne ,  Sam Tuck

IPC: B01L3/00 ,  C12N13/00

Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).

公开(公告)号：US20240066519A1

公开(公告)日：2024-02-29

申请号：US18381818

申请日：2023-10-19

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan Handique ,  Swati Ranade ,  Vishal Sharma ,  Austin Payne ,  Sam Tuck

IPC: B01L3/00 ,  C12N13/00

CPC classification number: B01L3/502 ,  C12N13/00 ,  B01L2200/026 ,  B01L2300/0893 ,  B01L2400/043

Abstract: A system and method for target material retrieval and processing, the system comprising: an adaptor configured to interface with a capture region of a capture substrate for capturing particles in single-particle format within a set of wells, wherein the adaptor comprises a first region configured to interface with the capture region, a second region, and a cavity extending from the first region to the second region; and a support structure coupled to the adaptor and providing a set of operation modes for movement of the adaptor relative to the capture substrate. The system enables methods for magnetic and/or other force-based methods of retrieval of target material (e.g., derived from single cells).