公开(公告)号：US20040170952A1

公开(公告)日：2004-09-02

申请号：US10043160

申请日：2002-01-14

Applicant: C.N.R.S. ,  I.N.R.A.

Inventor： Rima Zoorob ,  Charles Auffray ,  Anne-Marie Chausse

IPC: C12Q001/70 ,  C12Q001/68 ,  C07H021/04

CPC classification number: C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6869 ,  C12Q1/6883 ,  C12Q2600/156

Abstract: The invention relates to nucleic acid molecules which make it possible to detect those genes of the MHC involved in the phenomena of resistance or susceptibility to the development of virus-induced tumours. The primers developed from said molecules can be used in a method of genotyping farmed birds, and particularly chickens, characterised in that it comprises: amplification of a sample of nucleic acid originating from the animal to be studied using one or more pairs of primers capable of hybridising specifically with the nucleic acid of a polymorphic region of the Rfp-Y or B systems of the MHC of said birds, and detection of the PCR products obtained.

Abstract translation: 本发明涉及使得能够检测MHC参与抗病毒或对病毒诱导的肿瘤发展的易感性的那些基因的核酸分子。 从所述分子开发的引物可以用于对养殖的鸟，特别是鸡进行基因分型的方法，其特征在于，其包括：使用一种或多种能够进行研究的引物对来源于待研究的动物的核酸样品的扩增 与所述禽类的MHC的Rfp-Y或B系统的多态性区域的核酸特异性杂交，检测获得的PCR产物。