公开(公告)号：US20180020129A1

公开(公告)日：2018-01-18

申请号：US15588602

申请日：2017-05-06

Applicant: Center for Quantitative Cytometry

Inventor： Abraham Schwartz ,  Phillip Sherman ,  Peter Ingram

IPC: H04N5/217 ,  G01J3/28 ,  H04N5/232 ,  H04N9/09

CPC classification number: H04N5/2173 ,  G01J3/2823 ,  G01J2003/2826 ,  G06T5/002 ,  G06T5/50 ,  H04N5/217 ,  H04N5/23229 ,  H04N5/332 ,  H04N9/09

Abstract: The present invention is a method of removing the illumination and background spectral components thus isolating spectra from multi-spectral and hyper-spectral data cubes. The invention accomplishes this by first balancing a reference and sample data cubes for each spectra associated with each location, or pixel/voxel, in the spatial image. The set of residual spectra produced in the balancing step is used to obtain and correct a new set of reference spectra that is used to remove the illumination and background components in a sample data cube.