公开(公告)号：US20020082301A1

公开(公告)日：2002-06-27

申请号：US10029306

申请日：2001-12-20

Applicant: Cephalon, Inc.

Inventor： Matthew S. Miller ,  Thomas E. Scammell

IPC: A61K031/165

CPC classification number: G01N33/5088 ,  A61K31/165 ,  Y10S514/903

Abstract: Modafinil is effective in improving symptoms of attention deficit hyperactivity disorder and symptoms of multiple sclerosis fatigue. The administration of modafinil is also shown to activate the tuberomamillary neurons of the posterior hypothalamus, and thus exhibits activity in an area of the brain associated with normal wakefulness functions.

公开(公告)号：US20030069313A1

公开(公告)日：2003-04-10

申请号：US10283573

申请日：2002-10-30

Applicant: Cephalon, Inc.

Inventor： Matthew S. Miller ,  Thomas E. Scammell

IPC: A61K031/165

CPC classification number: G01N33/5088 ,  A61K31/165 ,  Y10S514/903

Abstract: Modafinil is effective in improving symptoms of attention deficit hyperactivity disorder and symptoms of multiple sclerosis fatigue. The administration of modafinil is also shown to activate the tuberomamillary neurons of the posterior hypothalamus, and thus exhibits activity in an area of the brain associated with normal wakefulness functions.