公开(公告)号：US20230389837A1

公开(公告)日：2023-12-07

申请号：US18143469

申请日：2023-05-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Venkatramanan Krishnamani ,  Anando Devadoss ,  Sahand Pirbadian ,  Nan Hu

IPC: A61B5/1486 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532

Abstract: A physiological sensor system that may include an analyte sensor configured to measure at least one analyte at varying depths at a tissue site of a user. The analyte sensor may include a plurality of electrodes patterned on a semi-rigid substrate meant to penetrate the skin of a user. The substrate may be varying lengths to increase the number of electrodes at the penetration site of the user and decrease the likelihood of a bad reading due to poor placement of the electrodes. The electrodes may be patterned on both sides of the substrate to increase number of measurement sites. The analyte sensor can be positioned in an electrochemical cell disposed in the body of the user.

公开(公告)号：US20220151521A1

公开(公告)日：2022-05-19

申请号：US17528630

申请日：2021-11-17

Applicant: Cercacor Laboratories, Inc.

Inventor： Venkatramanan Krishnamani ,  Sahand Pirbadian ,  Kevin Hughes Pauley ,  Sergei Petrovich Balashov ,  Anando Devadoss

IPC: A61B5/145 ,  G16H20/17 ,  A61B5/1486 ,  G01N27/327

Abstract: Embodiments of the present disclosure relate to a temperature independent glucose sensor and methods of making the same. Such glucose monitoring device may comprise a working electrode, a reference electrode, an glucose oxidase containing enzymatic layer, a first permeability-selective layer, an oxygen-replenishing layer, and an outer protective layer. Additional embodiments relate to a glucose sensor having an enzymatic layer containing glucose oxidase and a polymeric mediator. The sensors may be used as an implantable continuous glucose monitoring device without the need of a temperature sensor.