公开(公告)号：US12299885B2

公开(公告)日：2025-05-13

申请号：US18531500

申请日：2023-12-06

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06K9/00 ,  A61B5/00 ,  G06T7/00 ,  G06T7/62

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20240266064A1

公开(公告)日：2024-08-08

申请号：US18614586

申请日：2024-03-22

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G16H50/30 ,  A61B5/00 ,  A61B5/02 ,  G06T7/00 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40

CPC classification number: G16H50/30 ,  A61B5/02028 ,  A61B5/4848 ,  G06T7/0016 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V2201/031

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.

公开(公告)号：US11922627B2

公开(公告)日：2024-03-05

申请号：US18454462

申请日：2023-08-23

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06K9/00 ,  G06T7/00 ,  A61B5/00 ,  G06T7/62

CPC classification number: G06T7/0012 ,  A61B5/7275 ,  G06T7/62 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30101

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20230401711A1

公开(公告)日：2023-12-14

申请号：US18456341

申请日：2023-08-25

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06T7/00 ,  A61B5/00 ,  G06T7/62

CPC classification number: G06T7/0012 ,  A61B5/7275 ,  G06T7/62 ,  G06T2207/10108 ,  G06T2207/10101 ,  G06T2207/10081 ,  G06T2207/30101 ,  G06T2207/20081 ,  G06T2207/10104 ,  G06T2207/10116 ,  G06T2207/10048 ,  G06T2207/10132

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20240266066A1

公开(公告)日：2024-08-08

申请号：US18614595

申请日：2024-03-22

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G16H50/30 ,  A61B5/00 ,  A61B5/02 ,  G06T7/00 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40

CPC classification number: G16H50/30 ,  A61B5/02028 ,  A61B5/4848 ,  G06T7/0016 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V2201/031

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.

公开(公告)号：US20240266063A1

公开(公告)日：2024-08-08

申请号：US18614580

申请日：2024-03-22

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G16H50/30 ,  A61B5/00 ,  A61B5/02 ,  G06T7/00 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40

CPC classification number: G16H50/30 ,  A61B5/02028 ,  A61B5/4848 ,  G06T7/0016 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V2201/031

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.

公开(公告)号：US20230394663A1

公开(公告)日：2023-12-07

申请号：US18454462

申请日：2023-08-23

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06T7/00 ,  A61B5/00 ,  G06T7/62

CPC classification number: G06T7/0012 ,  A61B5/7275 ,  G06T7/62 ,  G06T2207/10108 ,  G06T2207/10101 ,  G06T2207/10132 ,  G06T2207/30101 ,  G06T2207/20081 ,  G06T2207/10104 ,  G06T2207/10116 ,  G06T2207/10048 ,  G06T2207/10081

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20230394662A1

公开(公告)日：2023-12-07

申请号：US18454364

申请日：2023-08-23

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06T7/00 ,  A61B5/00 ,  G06T7/62

CPC classification number: G06T7/0012 ,  A61B5/7275 ,  G06T7/62 ,  G06T2207/10108 ,  G06T2207/10101 ,  G06T2207/10081 ,  G06T2207/30101 ,  G06T2207/20081 ,  G06T2207/10104 ,  G06T2207/10116 ,  G06T2207/10048 ,  G06T2207/10132

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20230289963A1

公开(公告)日：2023-09-14

申请号：US18179921

申请日：2023-03-07

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G06T7/00 ,  G06T7/62 ,  A61B5/00

CPC classification number: G06T7/0012 ,  G06T7/62 ,  A61B5/7275 ,  G06T2207/30101 ,  G06T2207/20081 ,  G06T2207/10081 ,  G06T2207/10108 ,  G06T2207/10104 ,  G06T2207/10101 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/10048

Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.

公开(公告)号：US20240266068A1

公开(公告)日：2024-08-08

申请号：US18614605

申请日：2024-03-22

Applicant: Cleerly, Inc.

Inventor： James K. Min ,  James P. Earls ,  Shant Malkasian ,  Hugo Miguel Rodrigues Marques ,  Chung Chan ,  Shai Ronen

IPC: G16H50/30 ,  A61B5/00 ,  A61B5/02 ,  G06T7/00 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40

CPC classification number: G16H50/30 ,  A61B5/02028 ,  A61B5/4848 ,  G06T7/0016 ,  G06T7/10 ,  G06T7/60 ,  G06V20/50 ,  G16H30/40 ,  G06T2207/10048 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V2201/031

Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.