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公开(公告)号：US3743713A
公开(公告)日：1973-07-03
申请号：US3743713D
申请日：1971-06-22
IPC分类号： C07D307/885 , C09B11/08 , A61K27/04
CPC分类号： C07D307/885 , C09B11/08
摘要： A METHOD OF PREPARING RADIOACTIVE MONO AND DI-IODOSULFOBROMOPHTHALEIN FOR CLINICAL PURPOSES AND WHEREIN THE RATIO OF DI TO MONOIOSOSUFOBROMOPHTHALEIN CAN BE CONTROLLED IS DISCLOSED. NO SEPARATION AND PURIFICATION OF THE COMPOUNDS IS REQUIRED FOR THEIR USE IN CLINICAL DIAGNOSTIC PROCEDURES. THE COMPOUNDS, PARTICULARLY THE MONOIODO COMPOUND, OFFER A NUMBER OF ADVANTAGES IN COMPARISON TO SULFOBROMOPHTHALEIN WHEN USED FOR BIOLOGICAL INVESTIGATION.
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公开(公告)号：US3740558A
公开(公告)日：1973-06-19
申请号：US3740558D
申请日：1971-02-17
CPC分类号： G21G4/06 , G21G1/0005 , G21H5/00
摘要： A radioactive isotope generator for conducting parent-daughter radio-nuclide separations and containing a relatively small amount of radioactivity, the generator comprising a container or column having a parent nuclide disposed therein, the parent nuclide being separated from the remainder of the column by a filter material. As a specific embodiment, the generator comprises a column having two chambers separated by a filter material, the parent activity being adsorbed on an adsorbent such as alumina and being disposed in one of the chambers as a suspension. The open end of the column proximate the empty chamber is sealed by a puncturable stopper. By evacuating the empty chamber by means of a syringe inserted through the puncturable stopper, for example, the solution containing the daughter nuclide will pass through the filter and into the empty chamber, from which it is available for use.
摘要翻译： 一种放射性同位素发生器，用于进行母子放射性核素分离并含有相对少量的放射性，该发生器包括容纳在其中的母体核的柱或柱，母体核素通过过滤器与柱的其余部分分离 材料。 作为具体实施方案，发生器包括具有由过滤材料分离的两个室的柱，所述亲本活性被吸附在诸如氧化铝的吸附剂上，并且作为悬浮液设置在其中一个室中。 靠近空腔的柱的开口端由可穿刺的塞子密封。 通过例如通过可穿刺塞子插入的注射器排空空腔，含有子核素的溶液将通过过滤器并进入空室，从而可以使用它。
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