PROCESS FOR THE SYNTHESIS OF 3-HYDROXYGLUTARONITRILE
    4.
    发明申请
    PROCESS FOR THE SYNTHESIS OF 3-HYDROXYGLUTARONITRILE 有权
    3-羟基吡喃酮的合成方法

    公开(公告)号:US20120309931A1

    公开(公告)日:2012-12-06

    申请号:US13584904

    申请日:2012-08-14

    申请人: JELENA CIRAKOVIC

    发明人: JELENA CIRAKOVIC

    CPC分类号: C07C253/14 C07C255/12

    摘要: A high yield and high productivity processes for preparing 3-hydroxyglutaronitrile by reacting an epihalohydrin or a 4-halo-3-hydroxy-butanenitrile, or analogous compound containing a different leaving group, with cyanide (CN—) in the presence of water and an ionic liquid. The use of an ionic liquid as a cosolvent with water results in increased productivity and selectivity.

    摘要翻译: 通过使表卤代醇或4-卤代-3-羟基丁腈或含有不同离去基团的类似化合物与氰化物(CN-)在水存在下反应制备3-羟基戊二腈的高产率和高生产率方法, 离子液体。 使用离子液体作为助溶剂与水导致提高的生产率和选择性。