Tunable excitation and/or tunable detection microplate reader
    1.
    发明授权
    Tunable excitation and/or tunable detection microplate reader 失效
    可调谐激发和/或可调检测酶标仪

    公开(公告)号:US5784152A

    公开(公告)日:1998-07-21

    申请号:US729111

    申请日:1996-10-11

    摘要: A method and apparatus of analyzing samples contained in a microplate is provided. The instrument is capable of measuring fluorescence, luminescence, and/or absorption within multiple locations within a sample well. The instrument is tunable over the excitation and/or detection wavelengths. Neutral density filters are used to extend the sensitivity range of the absorption measuring aspect of the instrument. Due to the wavelength tuning capabilities of the instrument, the spectral dependence of the measured fluorescence, luminescence, and absorption of the materials in question can be analyzed. The combination of a data processor and a look-up table improve the ease of operation of the instrument. Several different formats are available for the output data including creation of a bit map of the sample.

    摘要翻译: 提供了分析微孔板中包含的样品的方法和装置。 该仪器能够测量样品井内多个位置的荧光,发光和/或吸收。 仪器可以在激发和/或检测波长上调谐。 中性密度滤波器用于扩展仪器吸收测量方面的灵敏度范围。 由于仪器的波长调谐能力,可以分析所测材料的测量荧光,发光和吸收的光谱依赖性。 数据处理器和查找表的组合可以提高仪器的操作性。 输出数据可以使用几种不同的格式,包括创建样本的位图。

    Microplate scanning read head
    2.
    发明授权
    Microplate scanning read head 有权
    微孔板扫描读头

    公开(公告)号:US06024920A

    公开(公告)日:2000-02-15

    申请号:US291787

    申请日:1999-04-14

    申请人: Chris Cunanan

    发明人: Chris Cunanan

    摘要: A scanning head assembly is provided, the scanning head suited for use with instruments that characterize the absorption, fluorescence, and/or luminescence properties of one or more samples contained within a sample plate or microplate. The scanning head assembly is coupled to a pair of scanning mechanisms, thereby allowing the head assembly to be raster scanned along both the x- and y-axis. Although the scanning preferably follows a serpentine pattern, other scan patterns can be utilized. Single or multiple measurements can be made per sample well, multiple measurements either being reported individually or averaged together. Although the scanning head assembly can utilize a variety of configurations, in the preferred embodiment the scanning head assembly has a C-shape with the light source and associated optics mounted in the lower arm of the assembly and the detector and associated optics mounted in the upper arm. Preferably the optics associated with the source include one or more optical filters that regulate the wavelength of light radiating the sample.

    摘要翻译: 提供扫描头组件,扫描头适用于表征样品板或微板中所含的一种或多种样品的吸收,荧光和/或发光特性的仪器。 扫描头组件耦合到一对扫描机构,从而允许头部组件沿x轴和y轴沿光栅扫描。 虽然扫描优选地遵循蛇形图案,但是可以利用其他扫描图案。 可以对每个样品进行单次或多次测量,多次测量单独报告或一起平均。 尽管扫描头组件可以利用各种配置,但是在优选实施例中,扫描头组件具有C形,其中光源和相关联的光学器件安装在组件的下臂中,并且检测器和相关联的光学器件安装在上部 臂。 优选地,与源相关联的光学器件包括调节辐射样品的光的波长的一个或多个滤光器。