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    NONINVASIVE MEASUREMENT OF CAROTENOIDS IN BIOLOGICAL TISSUE
    1.
    发明申请
    NONINVASIVE MEASUREMENT OF CAROTENOIDS IN BIOLOGICAL TISSUE 审中-公开
    生物组织中非生物活性测定

    公开(公告)号：US20120330164A1

    公开(公告)日：2012-12-27

    申请号：US13602798

    申请日：2012-09-04

    申请人： Igor V. Ermakov ,  Werner Gellerman

    发明人： Igor V. Ermakov ,  Werner Gellerman

    IPC分类号： A61B6/00

    CPC分类号： A61B5/0075 ,  A61B5/0053 ,  A61B5/443 ,  G01N21/4785 ,  G01N21/65 ,  G01N2021/4709 ,  G01N2021/4742 ,  G01N2021/4757 ,  G01N2021/656 ,  G01N2201/0221 ,  G01N2201/0618

    摘要： A method and apparatus are provided for the determination of carotenoid antioxidants and similar chemical compounds in biological tissue such as living skin. The method and apparatus provide a noninvasive, rapid, accurate, and safe determination of carotenoid levels which in turn can provide diagnostic information of the antioxidant status of tissue. Reflection spectroscopy is used to measure the concentrations of carotenoids and similar substances in tissue. White light is directed upon the area of tissue that is of interest. A small fraction of diffusively scattered light is collected and measured. The tissue is pressured to temporarily squeeze blood out of the measured tissue volume while the reflection spectrum is continuously monitored, displayed, and analyzed in near real time. After an optimal time period of typically 15 seconds, the influence of the dominating hemoglobin and oxyhemoglobin tissue absorptions on the reflection spectra are minimized.

    摘要翻译： 提供了一种方法和装置，用于测定生物组织如活皮中的类胡萝卜素抗氧化剂和类似化合物。 该方法和装置提供无创，快速，准确和安全的类胡萝卜素水平的测定，这又可以提供组织的抗氧化状态的诊断信息。 反射光谱法用于测量组织中类胡萝卜素和类似物质的浓度。 白光指向感兴趣的组织区域。 收集并测量一小部分漫射散射光。 对组织进行加压以暂时将血液挤出测量的组织体积，同时连续监测，显示和近实时分析反射光谱。 在最佳时间段通常为15秒后，主要血红蛋白和氧合血红蛋白组织吸收对反射光谱的影响最小化。

    SORTING METHOD AND APPARATUS
    2.
    发明申请
    SORTING METHOD AND APPARATUS 有权
    分类方法和装置

    公开(公告)号：US20120074047A1

    公开(公告)日：2012-03-29

    申请号：US13141863

    申请日：2009-12-21

    申请人： Benedict Deefholts

    发明人： Benedict Deefholts

    IPC分类号： B07C5/34 ,  G01N21/55

    CPC分类号： B07C5/368 ,  B07C5/342 ,  G01N21/314 ,  G01N21/359 ,  G01N21/85 ,  G01N21/94 ,  G01N33/025 ,  G01N2021/8592 ,  G01N2201/0618 ,  Y10S209/939

    摘要： A method of and apparatus for sorting foreign matter from a flow, the method comprising the steps of: identifying objects within a flow; for each identified object, determining reflectance intensities at at least two different wavelengths or ranges of wavelengths; and for each identified object, comparing the reflectance intensities at the at least two different wavelengths or ranges of wavelengths to a reference intensity profile, wherein the identified object is characterized as foreign matter when the reflectance intensities at the at least two different wavelengths or ranges of wavelengths fall within a predetermined region of the reference intensity profile.

    摘要翻译： 一种用于从流中分选异物的方法和装置，所述方法包括以下步骤：识别流内的物体; 对于每个识别的对象，确定至少两个不同波长或波长范围的反射率强度; 并且对于每个识别的对象，将至少两个不同波长或波长范围的反射强度与参考强度分布进行比较，其中当所述至少两个不同波长或范围内的反射强度为 波长落在参考强度分布的预定区域内。

    APPARATUS FOR PHOTODYNAMIC THERAPY AND PHOTODETECTION
    3.
    发明申请
    APPARATUS FOR PHOTODYNAMIC THERAPY AND PHOTODETECTION 有权
    光电疗法和光电保护装置

    公开(公告)号：US20100145416A1

    公开(公告)日：2010-06-10

    申请号：US12473745

    申请日：2009-05-28

    申请人： Uk KANG ,  Garri. V Papayan

    发明人： Uk KANG ,  Garri. V Papayan

    IPC分类号： A61N5/067 ,  A61N5/06

    CPC分类号： G01N21/6486 ,  A61B5/0059 ,  A61N5/0601 ,  A61N5/062 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0248 ,  G01J3/10 ,  G01J3/12 ,  G01J3/36 ,  G01J3/4406 ,  G01N21/255 ,  G01N21/29 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/6456 ,  G01N2201/0618

    摘要： The present invention provides an apparatus for photodynamic therapy and fluorescence detection, in which a combined light source is provided to illuminate an object body and a multispectral fluorescence-reflectance image is provided to reproduce various and complex spectral images for an object tissue, thus performing effective photodynamic therapy for various diseases both outside and inside of the body.For this purpose, the present invention provides an apparatus for photodynamic therapy and photodetection, which provides illumination with light of various wavelengths and multispectral images, the apparatus including: an optical imaging system producing an image of an object tissue and transmitting the image to a naked eye or an imaging device; a combined light source including a plurality of coherent and non-coherent light sources and a light guide guiding incident light emitted from the light sources; a multispectral imaging system including at least one image sensor; and a computer system outputting an image of the object tissue to the outside. Thus, the apparatus for photodynamic therapy and photodetection of the present invention can effectively perform the photodynamic therapy and photodetection by means of the combined light source capable of irradiating light having various spectral components to an object tissue and the multispectral imaging system capable of obtaining images from several spectral portions for these various spectral ranges at the same time, thus improving the accuracy of diagnosis and efficiency of the photodynamic therapy.

    摘要翻译： 本发明提供了一种用于光动力学治疗和荧光检测的装置，其中提供组合光源以照射物体，并且提供多光谱荧光反射图像以再现对象组织的各种和复杂的光谱图像，从而执行有效 身体各种疾病的光动力治疗。 为此，本发明提供了一种用于光动力学治疗和光电检测的装置，其提供具有各种波长和多光谱图像的光的照明，所述装置包括：光学成像系统，其产生对象组织的图像并将图像发送到裸体 眼睛或成像装置; 包括多个相干和非相干光源的组合光源和引导从光源发射的入射光的光导; 包括至少一个图像传感器的多光谱成像系统; 以及将对象组织的图像输出到外部的计算机系统。 因此，本发明的光动力学治疗和光电检测装置可以通过能够将具有各种光谱成分的光照射到对象组织上的组合光源和能够获得图像的多光谱成像系统而有效地进行光动力学治疗和光电检测 同时对于这些不同光谱范围的几个光谱部分，从而提高光动力疗法的诊断准确性和效率。

    METHOD AND A MACHINE FOR BALANCING VEHICLE WHEELS
    4.
    发明申请
    METHOD AND A MACHINE FOR BALANCING VEHICLE WHEELS 有权
    用于平衡车轮的方法和机器

    公开(公告)号：US20100005883A1

    公开(公告)日：2010-01-14

    申请号：US12439434

    申请日：2007-05-08

    申请人： Remo Corghi

    发明人： Remo Corghi

    IPC分类号： G01M1/32

    CPC分类号： G01N21/255 ,  G01B11/2522 ,  G01N21/85 ,  G01N2201/0221 ,  G01N2201/0224 ,  G01N2201/0618 ,  G01N2201/0692 ,  G01N2201/0694 ,  G01N2201/0696 ,  G06T7/521

    摘要： A method and a machine for balancing vehicle wheels with weights (18), the method comprising stages of: using a video camera (5, 6, 206) to frame a portion of a surface of a hub (101) of a wheel on which a weight (18) is to be applied, locating, in images of the hub (101) taken by the camera (5, 6, 206), at least a balancing plane (E1, E2) which is perpendicular to a rotation axis (A) of the wheel, piloting at least a pick-up device (8, 9, 209) such as to direct the at least a pick-up device (8, 9, 209) onto a point (P1, P2) of the hub (101) belonging to the balancing plane (E1, E2), detecting, by means of the pick-up device (8, 9, 209) characteristic geometric parameters of the hub (101) at the balancing plane (E1, E2), measuring an imbalance of the wheel, calculating, by means of an electronic calculator (4, 204) an entity of at least a weight (18) to be applied to the hub (101) at the balancing plane (E1, E2), and also calculating an angular position (T1, T2) of the weight (18) in the balancing plane (E1, E2).

    摘要翻译： 一种用于平衡车轮与重物（18）的方法和机器，所述方法包括以下步骤：使用摄像机（5,6,206）来构成车轮的轮毂（101）的表面的一部分，其中轮 将重量（18）应用于定位在由照相机（5,60）取下的轮毂（101）的图像中，至少一个垂直于旋转轴线的平衡面（E1，E2） A），至少引导拾取装置（8,9,209），以将至少一个拾取装置（8,9,209）引导到所述至少一个拾取装置（8,9,209）的点（P1，P2）上， 通过所述拾取装置（8,9,209）检测所述轮毂（101）在所述平衡面（E1，E2）处的特征几何参数，所述轮毂（101）属于所述平衡平面（E1，E2） 测量车轮的不平衡，借助于电子计算器（4,204）计算要在平衡平面（E1，E2）处施加到轮毂（101）的至少一个重量（18）的实体， 并计算重量（18）在t中的角位置（T1，T2） 他平衡平面（E1，E2）。

    PORTABLE DEVICE FOR THE QUALITY CONTROL OF PRODUCTS
    5.
    发明申请
    PORTABLE DEVICE FOR THE QUALITY CONTROL OF PRODUCTS 审中-公开
    便携式设备，用于产品质量控制

    公开(公告)号：US20090027669A1

    公开(公告)日：2009-01-29

    申请号：US12162463

    申请日：2006-03-24

    申请人： Bruno Zauli ,  Marco Remondini ,  Gildo Bosi

    发明人： Bruno Zauli ,  Marco Remondini ,  Gildo Bosi

    IPC分类号： G01N21/25

    CPC分类号： G01N21/474 ,  G01N21/255 ,  G01N33/02 ,  G01N33/025 ,  G01N2021/4757 ,  G01N2021/4759 ,  G01N2021/4761 ,  G01N2021/8466 ,  G01N2201/0221 ,  G01N2201/0224 ,  G01N2201/0618 ,  G01N2201/0636 ,  G01N2201/0692 ,  G01N2201/0694 ,  G01N2201/0696

    摘要： A portable device for the quality control of vegetal products comprising a power supply (7) intended for powering a circular crown of lighting lamps (41) at the centre of which there is arranged the receiving objective of a spectrometer (45) provided with means (431) adapted for resting on the product to be checked, said spectrometer (45) being associated to a microprocessor (11) which provides the measurement data on display means (12); according to the invention, the lamps (41) are permanently powered, and in stand-by, at a reduced voltage (70), lower than the nominal voltage (71) delivered by the power supply (7), and instantaneously at the nominal voltage (71 supplied by the power supply (7) through a power circuit (8) whose activation is commanded and controlled by the microprocessor (11) in response to an activation signal generated by a button (10).

    摘要翻译： 一种用于植物产品质量控制的便携式装置，包括用于为其中心处的照明灯（41）的圆形顶冠供电的电源（7），其中布置有设置有装置的光谱仪（45）的接收目标 431），其适于搁置在要检查的产品上，所述光谱仪（45）与在显示装置（12）上提供测量数据的微处理器（11）相关联; 根据本发明，灯（41）被永久地供电并且处于低于由电源（7）传送的标称电压（71）的低电压（70）的待机状态，并且瞬时地以标称 电压（71）由电源电路（8）提供，其电源电路（8）由微处理器（11）响应于由按钮（10）产生的激活信号而被命令和控制。

    ANALYZING APPARATUS
    6.
    发明申请
    ANALYZING APPARATUS 有权
    分析装置

    公开(公告)号：US20080285025A1

    公开(公告)日：2008-11-20

    申请号：US12121120

    申请日：2008-05-15

    申请人： Sakuichiro ADACHI

    发明人： Sakuichiro ADACHI

    IPC分类号： G01J3/00

    CPC分类号： G01N21/253 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/0262 ,  G01J3/04 ,  G01J3/36 ,  G01J3/42 ,  G01N21/13 ,  G01N21/255 ,  G01N2021/0325 ,  G01N2021/115 ,  G01N2021/3155 ,  G01N2201/0415 ,  G01N2201/0446 ,  G01N2201/0453 ,  G01N2201/0618

    摘要： A light amount is increased and an analyzing accuracy can be kept in accordance with an enlargement of a load angle, however, a scattered light tends to be loaded in an analysis accompanying the scattered light and a dynamic range of a concentration which can be measured becomes narrow. A light is dispersed by a light dispersing portion, a load angle of the received light is changed per wavelength, the load angle is made larger in the light of a wavelength having a small light amount, and the load angle is made smaller in the light a wavelength having a large light amount and used for an analysis accompanying a scattered light. Accordingly, it is possible to gain a dynamic range of a concentration which can be measured in the analysis accompanying the scattered light, while increasing the light amount and maintaining the analyzing accuracy.

    摘要翻译： 光量增加，并且可以根据负载角的放大来保持分析精度，然而，伴随散射光的分析倾向于加载散射光，并且可测量的浓度的动态范围变为 狭窄。 通过光分散部分散射光，每波长改变接收光的负载角度，在具有小光量的波长的光中使负载角变大，并且使光的负载角变小 具有大光量的波长并用于伴随散射光的分析。 因此，在增加光量并保持分析精度的同时，可以获得在伴随散射光的分析中可以测量的浓度的动态范围。

    Manufacturing method of semiconductor substrate and method and apparatus for inspecting defects of patterns of an object to be inspected
    8.
    发明授权
    Manufacturing method of semiconductor substrate and method and apparatus for inspecting defects of patterns of an object to be inspected 失效
    半导体基板的制造方法以及检查被检查体的图案的缺陷的方法和装置

    公开(公告)号：US06263099B1

    公开(公告)日：2001-07-17

    申请号：US09107432

    申请日：1998-06-30

    申请人： Shunji Maeda ,  Yasuhiko Nakayama ,  Minoru Yoshida ,  Hitoshi Kubota ,  Kenji Oka

    发明人： Shunji Maeda ,  Yasuhiko Nakayama ,  Minoru Yoshida ,  Hitoshi Kubota ,  Kenji Oka

    IPC分类号： G06K900

    CPC分类号： G01N21/8806 ,  G01N21/9501 ,  G01N21/956 ,  G01N21/95607 ,  G01N2021/95615 ,  G01N2201/0618 ,  G01N2201/0634

    摘要： A pattern detection method and apparatus thereof for inspecting with high resolution a micro fine defect of a pattern on an inspected object and a semiconductor substrate manufacturing method and system for manufacturing semiconductor substrates such as semiconductor wafers with a high yield. A micro fine pattern on the inspected object is inspected by irradiating an annular-looped illumination through an objective lens onto a wafer mounted on a stage, the wafer having micro fine patterns thereon. The illumination light may be circularly or elliptically polarized and controlled according to an image detected on the pupil of the objective lens and image signals are obtained by detecting a reflected light from the wafer. The image signals are compared with reference image signals and a part of the pattern showing inconsistency is detected as a defect so that simultaneously, a micro fine defect or defects on the micro fine pattern are detected with high resolution. Further, process conditions of a manufacturing line are controlled by analyzing a cause of defect and a factor of defect which occurs on the pattern.

    摘要翻译： 一种用于以高分辨率检查被检查物体上的图案的微细缺陷的图案检测方法及其装置以及以高产率制造半导体晶片等半导体基板的半导体基板的制造方法和系统。 通过将通过物镜的环形照明照射到安装在台架上的晶片上，检查被检查物体上的微细图案，晶片上具有微细精细图案。 照明光可以根据在物镜的光瞳上检测到的图像而被圆形或椭圆偏振并且被控制，并且通过检测来自晶片的反射光来获得图像信号。 将图像信号与参考图像信号进行比较，并且检测出显示不一致的图案的一部分作为缺陷，从而同时以高分辨率检测微细微图案或微细图案上的缺陷。 此外，通过分析缺陷的原因和在图案上发生的缺陷因素来控制生产线的工艺条件。