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公开(公告)号:US20180148454A1
公开(公告)日:2018-05-31
申请号:US15577518
申请日:2016-05-30
发明人: Honglin LI , Yufang XU , Zhenjiang ZHAO , Wei ZHOU , Yuqiong XU , Deheng SUN , Xia WANG , Zhuo CHEN
IPC分类号: C07D487/04 , A61P35/00 , A61P35/02
CPC分类号: C07D487/04 , A61K31/519 , A61P35/00 , A61P35/02 , C07D475/00
摘要: The present invention relates to a pteridinone derivative serving as an EGFR inhibitor and use thereof. Specifically, the present invention relates to a compound represented by the following formula I, pharmaceutical composition comprising the compound of the following formula I, and use of the compound in preparation of drugs for treating EGFR-mediated diseases or inhibiting EGFR.