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公开(公告)号：US20210355159A1
公开(公告)日：2021-11-18
申请号：US17311099
申请日：2019-11-11
Applicant: EMD Millipore Corporation
Inventor： Thomas Elich , Herbert Lutz
Abstract: Method and system for purifying a sample comprising a biomolecule of interest and impurities, comprising expressing said biomolecule of interest in a bioreactor to form a product sample comprising said biomolecule of interest and impurities; subjecting said product sample to single pass tangential flow filtration to form a concentrated product sample; and subjecting said concentrated product sample to affinity chromatography to remove impurities from said concentrated product sample.
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