公开(公告)号：US12055530B2

公开(公告)日：2024-08-06

申请号：US17125222

申请日：2020-12-17

申请人： Elemental Scientific, Inc.

发明人： Alexander Lang ,  Brianna Dufek ,  Daniel R. Wiederin

IPC分类号： G01N30/00 ,  G01N30/72 ,  H01J49/00 ,  H01J49/04 ,  H01J49/10 ,  H01J49/40

CPC分类号： G01N30/724 ,  H01J49/0036 ,  H01J49/0422 ,  H01J49/045 ,  H01J49/105 ,  H01J49/40

摘要： An embodiment of an analysis system can include an initial multi-port valve, at least one intermediate multi-port valve, a further multi-port valve, and a time-of-flight mass spectrometer (TOF-MS). The initial multi-port valve can be configured to receive a sample. The at least one intermediate multi-port valve can be fluidly connected to the initial multi-port valve and configured to receive the sample from the initial multi-port valve. A given intermediate multi-port valve can have an ion-exchange column associated therewith. The given intermediate multi-port valve can be configured selectably to one of direct the sample through the ion-exchange column associated therewith (in a speciation mode) or bypass the ion-exchange column (in an infusion mode). The further multi-port valve can be fluidly connected with the at least one intermediate multi-port valve and configured to receive the sample from therefrom. The time-of-flight mass spectrometer (TOF-MS) can be fluidly connected to the further multi-port valve.

公开(公告)号：US20210181165A1

公开(公告)日：2021-06-17

申请号：US17125222

申请日：2020-12-17

申请人： Elemental Scientific, Inc.

发明人： Alexander Lang ,  Brianna Dufek ,  Daniel R. Wiederin

IPC分类号： G01N30/72 ,  H01J49/40 ,  H01J49/10 ,  H01J49/00 ,  H01J49/04

摘要： An embodiment of an analysis system can include an initial multi-port valve, at least one intermediate multi-port valve, a further multi-port valve, and a time-of-flight mass spectrometer (TOF-MS). The initial multi-port valve can be configured to receive a sample. The at least one intermediate multi-port valve can be fluidly connected to the initial multi-port valve and configured to receive the sample from the initial multi-port valve. A given intermediate multi-port valve can have an ion-exchange column associated therewith. The given intermediate multi-port valve can be configured selectably to one of direct the sample through the ion-exchange column associated therewith (in a speciation mode) or bypass the ion-exchange column (in an infusion mode). The further multi-port valve can be fluidly connected with the at least one intermediate multi-port valve and configured to receive the sample from therefrom. The time-of-flight mass spectrometer (TOF-MS) can be fluidly connected to the further multi-port valve.