公开(公告)号：US20210310031A1

公开(公告)日：2021-10-07

申请号：US17271474

申请日：2019-10-14

Applicant: FIRMENICH SA

Inventor： Daniel SOLIS ESCALANTE ,  Christian GÖRNER ,  Laurent DAVIET ,  Qi WANG

IPC: C12P7/62 ,  C12P7/02

Abstract: Described herein are novel methods for the acetyl transferase-catalyzed production of drimanyl-acetate compounds by the acetylation of the respective drimanyl alcohol sources performed in vitro or in vivo. Also described herein is the identification of enzymes having corresponding acetyl transferase activity from different microbial and plant sources. Also described herein is the provision of enzyme mutants derived from the newly identified enzymes. Further described herein is the provision of corresponding coding sequences of such enzymes and mutants, recombinant vectors, and recombinant host cells suitable for the production of such acetyl transferases and mutants and for performing the novel production methods of drimanyl acetate compounds. Still further described herein is a method of using such drimanyl acetates as intermediates for the production of odorant, flavor or fragrance or insect/pest control ingredients.