公开(公告)号：US20200215491A1

公开(公告)日：2020-07-09

申请号：US16822113

申请日：2020-03-18

Applicant: FUJIFILM CORPORATION

Inventor： Hidetoshi TAKAYAMA ,  Hiroshi YAMASHITA ,  Masumi MIYAJIMA

IPC: B01D63/08 ,  B01D69/06 ,  B01D69/10

Abstract: Provided is a filtration device including: a flow path that meanders; a filtration membrane that separates a supply side and a permeation side of the flow path; a first distribution port that is provided at one end of the supply side of the flow path; a second distribution port that is provided at the other end of the supply side of the flow path; a first discharge port that is provided on the permeation side of the flow path; and a second discharge port that is provided at a position different from that of the first discharge port on the permeation side of the flow path. First liquid feeding for allowing a liquid flowed in from the first distribution port to flow out from the second distribution port, and second liquid feeding for allowing a liquid flowed in from the second distribution port to flow out from the first distribution port are alternately performed. A liquid that has passed through the filtration membrane is discharged from the first discharge port while the first liquid feeding is performed, and a liquid that has passed through the filtration membrane is discharged from the second discharge port while the second liquid feeding is performed.

公开(公告)号：US20230238084A1

公开(公告)日：2023-07-27

申请号：US18192001

申请日：2023-03-29

Applicant: FUJIFILM Corporation

Inventor： Kyosuke TSUMURA ,  Hiroshi YAMASHITA ,  Jun NAKABAYASHI

IPC: G16C20/20 ,  G16C20/50

CPC classification number: G16C20/20 ,  G16C20/50

Abstract: According to one embodiment of the present invention, provided are a feature quantity calculating method which enables calculation of a feature quantity accurately showing chemical properties of a target structure, a screening method which enables efficient screening of a pharmaceutical candidate compound using a feature quantity, and a compound creating method which enable efficient creation of a three-dimensional structure of a pharmaceutical candidate compound using a feature quantity. In one aspect of the present invention, the feature quantity calculating method is a method including a target structure designating step of designating a target structure formed of a plurality of unit structures having chemical properties, a three-dimensional structure acquiring step of acquiring a three-dimensional structure from the plurality of unit structures for the target structure, and a probe feature quantity calculating step of calculating a feature quantity showing a cross-sectional area of one or more kinds of probes for the target structure, in which the probe is a structure in which a plurality of points having a real electric charge and generating a van der Waals force are disposed to be separated from each other.