公开(公告)号：US20200239495A1

公开(公告)日：2020-07-30

申请号：US16839563

申请日：2020-04-03

Applicant: FUJIFILM Corporation

Inventor： Muneo SHOJI ,  Kentaro FURUYA ,  Kei MATSUURA ,  Hiromi HAYASHI ,  Tetsuya MATSUSHITA ,  Hirofumi OMURA

IPC: C07D499/897

Abstract: An object of the present invention is to provide a compound and a pharmaceutical composition which exhibit strong antibacterial activity against Gram-negative bacteria and drug-resistant Gram-negative bacteria. According to the present invention, a compound represented by General Formula [1] (the reference signs in the formula have the same definitions as those described in the present specification) or a salt thereof has strong antibacterial activity against Gram-negative bacteria such as Pseudomonas aeruginosa and drug-resistant Gram-negative bacteria including multidrug-resistant Pseudomonas aeruginosa, and the pharmaceutical composition containing the compound or a salt thereof is useful as an antibacterial agent.

公开(公告)号：US20210024543A1

公开(公告)日：2021-01-28

申请号：US17063110

申请日：2020-10-05

Applicant: FUJIFILM Corporation

Inventor： Muneo SHOJI ,  Kentaro FURUYA ,  Kei MATSUURA ,  Tomofumi NAKAE

IPC: C07D499/897 ,  A61P31/04

Abstract: An object of the present invention is to provide a compound and a pharmaceutical composition which exhibit strong antibacterial activity against Gram-negative bacteria and drug-resistant Gram-negative bacteria. A compound represented by General Formula [1] (the reference signs in Formula have the same definitions as those described in the present specification) or a salt thereof has strong antibacterial activity against Gram-negative bacteria such as Pseudomonas aeruginosa and drug-resistant Gram-negative bacteria including multidrug-resistant Pseudomonas aeruginosa, and the pharmaceutical composition containing the compound or a salt thereof is useful as an antibacterial agent.