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公开(公告)号:US5037698A
公开(公告)日:1991-08-06
申请号:US145444
申请日:1988-01-19
申请人: Francois Brunel
发明人: Francois Brunel
IPC分类号: A61K9/48
CPC分类号: A61K9/4866 , A61K9/4858 , Y10S514/962 , Y10S514/963 , Y10T428/2984
摘要: Capsules containing a hygroscopic or deliquescent component are stabilized by a) forming a mixture of the hydrogscopic or deliquescent compound with a sufficient quantity of water to achieve an equilibrium, b) adding a thickening agent and c) heating the solution or suspension; and introducing the heated composition so formed into the capsule. Preferably an equilibrium-protecting agent, such as glycerin, is also added.