公开(公告)号：US20210338778A1

公开(公告)日：2021-11-04

申请号：US17162924

申请日：2021-01-29

Applicant: Genentech, Inc.

Inventor： Alexander R. ABBAS ,  Nico P. GHILARDI ,  Zora MODRUSAN ,  Dimitry M. DANILENKO ,  Frederic J. DE SAUVAGE ,  Wenjun OUYANG ,  Patricia A. VALDEZ ,  Yan ZHENG

IPC: A61K38/19 ,  A61K38/20 ,  A61K38/17

Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.

公开(公告)号：US20190062836A1

公开(公告)日：2019-02-28

申请号：US15924114

申请日：2018-03-16

Applicant: GENENTECH, INC.

Inventor： Alexander R. ABBAS ,  Joseph R. ARRON ,  Sanjay CHANDRIANI ,  Guiquan JIA ,  Nicholas J.I. LEWIN-KOH ,  Daryle DEPIANTO

IPC: C12Q1/6883 ,  G01N33/68 ,  C07K16/24 ,  A61K39/00 ,  A61K38/00

Abstract: Compositions, kits and methods for assessing the prognosis of idiopathic pulmonary fibrosis in patients are provided. In addition, compositions, kits and methods for diagnosing subtypes of idiopathic pulmonary fibrosis are provided. Also provided are methods for treating idiopathic pulmonary fibrosis.