公开(公告)号：US20230071609A1

公开(公告)日：2023-03-09

申请号：US17846744

申请日：2022-06-22

Applicant: Genentech Inc.

Inventor： Suzanna Jane Scales ,  Nidhi Gupta ,  Andrew Scott Peterson

IPC: C07K16/28 ,  G01N33/68

Abstract: This disclosure provides anti-apolipoprotein L1 (APOL1) antibodies, including anti-APOL1 antibodies that distinguish the GO and G1 forms from the G2 form of APOL1, distinguish APOL1 found on podocytes from that found on HDL particles in serum, and distinguish APOL1 from apolipoproteins L2, L3, L4 and L6 (APOL2, APOL3, APOL4 and APOL6), and methods of using the same.

公开(公告)号：US20140212431A1

公开(公告)日：2014-07-31

申请号：US14133986

申请日：2013-12-19

Applicant: Genentech, Inc.

Inventor： Daniel K. Kirchhofer ,  Yingnan Zhang ,  Andrew Scott Peterson ,  Wei Li ,  Monica Kong-Beltran ,  Lijuan Zhou

IPC: C07K16/40 ,  A61K45/06 ,  A61K39/395

CPC classification number: C07K16/40 ,  A61K31/40 ,  A61K38/1808 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  A61K2300/00 ,  C07K14/485 ,  C07K2317/70 ,  C07K2319/30 ,  C12N9/6454 ,  A61K31/22 ,  A61K31/365 ,  A61K31/366 ,  A61K31/404 ,  A61K31/505

Abstract: The invention provides PCSK9-binding polypeptides and methods of using the same.

Abstract translation: 本发明提供PCSK9结合多肽及其使用方法。