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公开(公告)号：US10421821B2
公开(公告)日：2019-09-24
申请号：US15336171
申请日：2016-10-27
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: A61K39/00 , A61K39/395 , C07K16/40
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号：US20190048097A1
公开(公告)日：2019-02-14
申请号：US16168503
申请日：2018-10-23
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
CPC classification number: C07K16/40 , A61K39/3955 , A61K2039/507 , C07K2317/24 , C07K2317/34 , C07K2317/53 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号：US20230383008A1
公开(公告)日：2023-11-30
申请号：US18048763
申请日：2022-10-21
Applicant: Genentech, Inc.
Inventor： Robert F. KELLEY , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: C07K16/40 , A61K39/395
CPC classification number: C07K16/40 , A61K39/3955 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/92 , C07K2317/94 , A61K2039/507
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号：US11512143B2
公开(公告)日：2022-11-29
申请号：US16543818
申请日：2019-08-19
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号：US10246519B2
公开(公告)日：2019-04-02
申请号：US15958977
申请日：2018-04-20
Applicant: Genentech, Inc.
Inventor： Shuo-Yen Jack Lin , Daniel K. Kirchhofer , Menno Van Lookeren Campagne
Abstract: The invention provides NSP4 inhibitors (such as anti-NSP4 antibodies) and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US20160355606A1
公开(公告)日：2016-12-08
申请号：US14981853
申请日：2015-12-28
Applicant: Genentech, Inc.
Inventor： Yan Wu , Cecilia Pui Chi Chiu , Daniel K. Kirchhofer , Andrew Peterson , Ganesh A. Kolumam , Monica Kong Beltran , Paul Moran , Wei Li , Xanthe Lam , Lin Luis , Ada Hui , Whittemore Tingley , John Douglas Davis , Nageshwar R. Budha
IPC: C07K16/40
CPC classification number: C07K16/40 , A61K39/39591 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides anti-PCSK9 antibodies, formulations, dosing regimens, and methods of using the same.
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公开(公告)号：US20150126448A1
公开(公告)日：2015-05-07
申请号：US14316621
申请日：2014-06-26
Applicant: Genentech, Inc.
Inventor： Daniel K. Kirchhofer , Robert A. Lazarus , Xiaoyi Yao
CPC classification number: A61K38/10 , C07K7/08 , C07K14/4753 , G01N33/57438 , G01N33/6863 , G01N33/6872 , G01N33/74 , G01N2333/4753 , G01N2500/02 , G01N2500/04
Abstract: The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating binding of HGF β chain to c-met.
Abstract translation: 本发明提供调节HGF / c-met信号通路的方法和组合物，特别是通过调节HGF和bgr的结合; 链到c-met。
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公开(公告)号：US10421822B2
公开(公告)日：2019-09-24
申请号：US16168503
申请日：2018-10-23
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号：US09975963B2
公开(公告)日：2018-05-22
申请号：US15094843
申请日：2016-04-08
Applicant: Genentech, Inc.
Inventor： Shuo-Yen Jack Lin , Daniel K. Kirchhofer , Menno Van Lookeren Campagne
CPC classification number: C07K16/40 , A61K2039/505 , C07K16/24 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/76 , C07K2317/92
Abstract: The invention provides NSP4 inhibitors (such as anti-NSP4 antibodies) and methods of using the same.
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公开(公告)号：US20170106042A1
公开(公告)日：2017-04-20
申请号：US15162372
申请日：2016-05-23
Applicant: Genentech, Inc.
Inventor： Daniel K. Kirchhofer , Robert A. Lazarus , Xiaoyi Yao
IPC: A61K38/10 , C07K14/475 , G01N33/68 , C07K7/08
CPC classification number: A61K38/10 , C07K7/08 , C07K14/4753 , G01N33/57438 , G01N33/6863 , G01N33/6872 , G01N33/74 , G01N2333/4753 , G01N2500/02 , G01N2500/04
Abstract: The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating binding of HGF β chain to c-met.
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