公开(公告)号：US20240094194A1

公开(公告)日：2024-03-21

申请号：US18518715

申请日：2023-11-24

Applicant: Genentech, Inc.

Inventor： Claudio CIFERRI ,  Evan Michael Green ,  Marc Kschonsak

IPC: G01N33/50 ,  G01N33/569

CPC classification number: G01N33/5091 ,  G01N33/56994 ,  C12N2503/00 ,  G01N2333/045 ,  G01N2469/10

Abstract: Provided herein are methods of treating or preventing human cytomegalovirus (HCMV) infection comprising modulating interactions between the HCMV gH/gL/UL128-131A pentamer and plasma membrane-expressed host cell proteins, as well as methods of identifying modulators of such interactions.