公开(公告)号：US11542308B2

公开(公告)日：2023-01-03

申请号：US17664589

申请日：2022-05-23

Applicant: Genentech, Inc.

Inventor： Yichin Liu ,  Christine Carine Moussion ,  Travis William Bainbridge ,  Iraj Hosseini ,  Gregory Alan Lazar ,  Sivan Cohen ,  Christopher Charles Kemball ,  Jill M. Schartner

IPC: C07K14/475 ,  A61K38/18 ,  A61K31/713 ,  A61K39/395 ,  C07K16/28 ,  A61K39/00

Abstract: The invention provides an effectorless immunoglobulin Fc protein, fusions of the effectorless Fc protein to a Flt3 ligand, and methods of using the same.

公开(公告)号：US20240409599A1

公开(公告)日：2024-12-12

申请号：US18669898

申请日：2024-05-21

Applicant: Genentech, Inc.

Inventor： Travis William Bainbridge ,  Beyza Bulutoglu Baykara ,  Jonathan Thomas Sockolosky

IPC: C07K14/54 ,  A61K38/00 ,  A61P35/00 ,  G01N33/53 ,  G01N33/68

Abstract: The invention provides stabilized IL-18 polypeptides and methods of making and using the same.