公开(公告)号：US20190015008A1

公开(公告)日：2019-01-17

申请号：US16027057

申请日：2018-07-03

Applicant: General Electric Company

Inventor： Azar Alizadeh ,  Andrew A. Burns ,  Matthew Jeremiah Misner ,  Ralf Lenigk ,  Jeffrey Michael Ashe ,  Obi Aghogho ,  Nancy Cecelia Stoffel ,  Juha Virtanen ,  Otto Pekander ,  Timo Toivanen ,  Robert Santala

IPC: A61B5/0408 ,  A61B5/00

Abstract: A system for monitoring medical conditions includes a conformable medical monitoring device that includes a first substrate layer, which includes an electronics module, many signal traces, and at least one electrode, such that one or more of the many signal traces electrically couple the at least one electrode to the electronics module. The conformable medical monitoring device includes a second substrate layer positioned over the electronics module, the first substrate layer, or any combination thereof to insulate the electronics module, the first substrate layer, or any combination thereof. The conformable medical monitoring device also includes a third substrate layer positioned over the second substrate layer, such that the third substrate layer reduces electromagnetic interference caused by a voltage pulse and includes an adjustable system coupled to the first substrate layer and that changes a position of the at least one electrode relative to the electronics module.

公开(公告)号：US20250064349A1

公开(公告)日：2025-02-27

申请号：US18456193

申请日：2023-08-25

Applicant: General Electric Company

Inventor： Andrew Arthur Paul Burns ,  Azar Alizadeh ,  Ralf Lenigk

IPC: A61B5/145 ,  A61B5/00

Abstract: A wearable interstitial fluid (ISF) sensing includes a first patch layer and an electronics module component layer. The electronics module component layer is laminated to the first patch layer to form a patch component and a plurality of microneedles extending from the patch component. The electronics module component layer includes a substrate and a sensor positioned on the substrate. Each microneedle of the plurality of microneedles includes a microneedle base extending from the patch component, a body extending from the microneedle base, and a tip extending from the body. The body defines a slot extending through the first patch layer of the body. The slot defines a first opening and a second opening. The at least one sensor is positioned over the second opening. The first opening, the slot, and the sensor define a channel exposed to the environment. The channel is configured to channel ISF to the sensor.

公开(公告)号：US20190019603A1

公开(公告)日：2019-01-17

申请号：US16026955

申请日：2018-07-03

Applicant: General Electric Company

Inventor： Azar Alizadeh ,  Matthew Jeremiah Misner ,  Andrew A. Burns ,  Juha Virtanen ,  Otto Pekander ,  Robert Santala ,  Teemu Alajoki

IPC: H01C1/16 ,  H01C7/00 ,  H01C1/14 ,  H01C17/065 ,  H01C1/08 ,  H05K1/16 ,  A61B5/0424 ,  A61B5/0408

Abstract: A system includes a conformable biopotential sensor that withstands a defibrillation pulse. The conformable biopotential sensor includes a polymer substrate, a plurality of electrodes printed on the polymer substrate, a signal trace printed on the polymer substrate, and one or more resistors printed on the polymer substrate and in electrical communication with an electrode of the plurality of electrodes via the signal trace. One or both of the one or more resistors and the polymer substrate withstand a defibrillation pulse. The conformable biopotential sensor further includes a coating layer applied to the one of both of the one or more resistors, wherein the coating is more thermally conductive than the polymer substrate.

公开(公告)号：US20250064348A1

公开(公告)日：2025-02-27

申请号：US18456146

申请日：2023-08-25

Applicant: General Electric Company

Inventor： Andrew Arthur Paul Burns ,  Azar Alizadeh ,  Ralf Lenigk ,  Richard JeanLuc St. Pierre

IPC: A61B5/145 ,  A61B5/00

Abstract: A microneedle actuator for monitoring ISF of a user includes a rigid support defining a slot, a geared cam positioned within the rigid support and including an axle extending through the slot, and a spring positioned within the rigid support and configured to rotate the geared cam about the axle. The microneedle actuator further includes an ISF sensing module and an actuation device. The ISF sensing module is attached to the geared cam and including a plurality of microneedles, each microneedle of the plurality of microneedles including at least one sensor for detecting the ISF of the user. The actuation device is attached to the rigid support and the geared cam. Actuation of the actuation device releases the spring, rotating the geared cam to insert the plurality of microneedles into the user's skin, and wherein the at least one sensor detects constituents of the ISF of the user.

公开(公告)号：US11311225B2

公开(公告)日：2022-04-26

申请号：US16027057

申请日：2018-07-03

Applicant: General Electric Company

Inventor： Azar Alizadeh ,  Andrew A. Burns ,  Matthew Jeremiah Misner ,  Ralf Lenigk ,  Jeffrey Michael Ashe ,  Obi Aghogho ,  Nancy Cecelia Stoffel ,  Juha Virtanen ,  Otto Pekander ,  Timo Toivanen ,  Robert Santala

IPC: A61B5/282 ,  A61B5/00 ,  A61B5/145 ,  A61B5/01

Abstract: A system for monitoring medical conditions includes a conformable medical monitoring device that includes a first substrate layer, which includes an electronics module, many signal traces, and at least one electrode, such that one or more of the many signal traces electrically couple the at least one electrode to the electronics module. The conformable medical monitoring device includes a second substrate layer positioned over the electronics module, the first substrate layer, or any combination thereof to insulate the electronics module, the first substrate layer, or any combination thereof. The conformable medical monitoring device also includes a third substrate layer positioned over the second substrate layer, such that the third substrate layer reduces electromagnetic interference caused by a voltage pulse and includes an adjustable system coupled to the first substrate layer and that changes a position of the at least one electrode relative to the electronics module.