MICRONEEDLE-INTEGRATED INTERSTITIAL FLUID BIOMARKER SENSOR SYSTEMS AND METHODS THEREOF

    公开(公告)号:US20250064349A1

    公开(公告)日:2025-02-27

    申请号:US18456193

    申请日:2023-08-25

    Abstract: A wearable interstitial fluid (ISF) sensing includes a first patch layer and an electronics module component layer. The electronics module component layer is laminated to the first patch layer to form a patch component and a plurality of microneedles extending from the patch component. The electronics module component layer includes a substrate and a sensor positioned on the substrate. Each microneedle of the plurality of microneedles includes a microneedle base extending from the patch component, a body extending from the microneedle base, and a tip extending from the body. The body defines a slot extending through the first patch layer of the body. The slot defines a first opening and a second opening. The at least one sensor is positioned over the second opening. The first opening, the slot, and the sensor define a channel exposed to the environment. The channel is configured to channel ISF to the sensor.

    WEARABLE DEVICE FOR ON-DEMAND INTERSTITIAL FLUID BIOMARKER SENSING WITH A MICRONEEDLE-INTEGRATED SENSOR

    公开(公告)号:US20250064348A1

    公开(公告)日:2025-02-27

    申请号:US18456146

    申请日:2023-08-25

    Abstract: A microneedle actuator for monitoring ISF of a user includes a rigid support defining a slot, a geared cam positioned within the rigid support and including an axle extending through the slot, and a spring positioned within the rigid support and configured to rotate the geared cam about the axle. The microneedle actuator further includes an ISF sensing module and an actuation device. The ISF sensing module is attached to the geared cam and including a plurality of microneedles, each microneedle of the plurality of microneedles including at least one sensor for detecting the ISF of the user. The actuation device is attached to the rigid support and the geared cam. Actuation of the actuation device releases the spring, rotating the geared cam to insert the plurality of microneedles into the user's skin, and wherein the at least one sensor detects constituents of the ISF of the user.

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