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1.发明授权公开(公告)号：US09511122B2
公开(公告)日：2016-12-06
申请号：US13515621
申请日：2010-12-15
CPC分类号： A61K38/27 , A61K9/0019 , A61K9/08 , A61K9/19 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/26 , A61K47/60 , A61M5/19
摘要： The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
摘要翻译： 本发明涉及含有冻干保护剂和任选的一种或多种赋形剂的rhGH聚合物前药的干组合物。 当2-8℃下储存时，这样的组合物至少存在1年是稳定的。本发明还涉及制备所述组合物的方法，包含这种组合物的容器以及一组成分。
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2.发明申请公开(公告)号：US20120322721A1
公开(公告)日：2012-12-20
申请号：US13515621
申请日：2010-12-15
CPC分类号： A61K38/27 , A61K9/0019 , A61K9/08 , A61K9/19 , A61K45/06 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/26 , A61K47/60 , A61M5/19
摘要： The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
摘要翻译： 本发明涉及含有冻干保护剂和任选的一种或多种赋形剂的rhGH聚合物前药的干组合物。 当2-8℃下储存时，这样的组合物至少存在1年是稳定的。本发明还涉及制备所述组合物的方法，包含这种组合物的容器以及一组成分。
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