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公开(公告)号:USD676378S1
公开(公告)日:2013-02-19
申请号:US29420934
申请日:2012-05-15
申请人: Hae-Jin Kim , Dae-Joung Kim , Sang-Min Hyun , Soo-Jung Lee
设计人: Hae-Jin Kim , Dae-Joung Kim , Sang-Min Hyun , Soo-Jung Lee
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公开(公告)号:USD742094S1
公开(公告)日:2015-11-03
申请号:US29424600
申请日:2012-06-13
申请人: Hae-Jin Kim , Dae-Joung Kim , Sang-Min Hyun , Soo-Jung Lee
设计人: Hae-Jin Kim , Dae-Joung Kim , Sang-Min Hyun , Soo-Jung Lee
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公开(公告)号:USD724527S1
公开(公告)日:2015-03-17
申请号:US29424598
申请日:2012-06-13
申请人: Soo-Jung Lee , Dae-Joung Kim , Sang-Min Hyun , Hae-Jin Kim
设计人: Soo-Jung Lee , Dae-Joung Kim , Sang-Min Hyun , Hae-Jin Kim
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公开(公告)号:USD724526S1
公开(公告)日:2015-03-17
申请号:US29424594
申请日:2012-06-13
申请人: Soo-Jung Lee , Dae-Joung Kim , Sang-Min Hyun , Hae-Jin Kim
设计人: Soo-Jung Lee , Dae-Joung Kim , Sang-Min Hyun , Hae-Jin Kim
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公开(公告)号:USD724525S1
公开(公告)日:2015-03-17
申请号:US29424589
申请日:2012-06-13
申请人: Soo-Jung Lee , Sang-Min Hyun , Dae-Joung Kim , Hae-Jin Kim
设计人: Soo-Jung Lee , Sang-Min Hyun , Dae-Joung Kim , Hae-Jin Kim
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公开(公告)号:USD687811S1
公开(公告)日:2013-08-13
申请号:US29419036
申请日:2012-04-24
申请人: Soo-Jung Lee , Sang-Min Hyun
设计人: Soo-Jung Lee , Sang-Min Hyun
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公开(公告)号:USD691572S1
公开(公告)日:2013-10-15
申请号:US29418227
申请日:2012-04-13
申请人: Soo-Jung Lee , Sang-Min Hyun
设计人: Soo-Jung Lee , Sang-Min Hyun
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公开(公告)号:USD604711S1
公开(公告)日:2009-11-24
申请号:US29333459
申请日:2009-03-10
申请人: Soo-Jung Lee , Beom-Ku Han , Chang-Hwan Hwang
设计人: Soo-Jung Lee , Beom-Ku Han , Chang-Hwan Hwang
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公开(公告)号:USD582884S1
公开(公告)日:2008-12-16
申请号:US29301765
申请日:2008-03-14
申请人: Soo-Jung Lee , Beom-Ku Han , Chang-Soo Lee
设计人: Soo-Jung Lee , Beom-Ku Han , Chang-Soo Lee
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公开(公告)号:US09095535B2
公开(公告)日:2015-08-04
申请号:US13389981
申请日:2010-08-24
申请人: Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
发明人: Changjoon Justin Lee , Soo-Jung Lee , Bo-Eun Yoon
IPC分类号: A61K49/00 , A61P25/00 , A61P25/28 , A61P25/32 , A61P25/08 , G01R27/28 , A61K31/00 , A61K31/185 , A61K31/196 , A61K31/455 , A61K31/7105 , A61K31/713 , A61K38/04 , A61K38/08 , G01N33/94
CPC分类号: A61K31/00 , A61K31/185 , A61K31/196 , A61K31/455 , A61K31/7105 , A61K31/713 , A61K38/043 , A61K38/08 , G01N33/9426 , G01N2500/10
摘要: A GABA (gamma-aminobutyric acid) release-inhibiting agent in the cerebellum and a composition for treating pathological symptoms caused by over-release of GABA in the cerebellum, each comprising a Bestrophin 1 (Best1) channel inhibitor as an active ingredient; a GABA release-promoting agent in the cerebellum and a composition for treating pathological symptoms caused by the deficit of GABA in the cerebellum, each comprising a Best1 channel activator as an active ingredient; and a method for screening a GABA release-regulating agent in the cerebellum, which uses Best1 channel as target, are provided.
摘要翻译: 小脑中的GABA(γ-氨基丁酸)释放抑制剂和用于治疗由小脑中的GABA过度释放引起的病理学症状的组合物,每种包含Bestrophin 1(Best1)通道抑制剂作为活性成分; 小脑中的GABA释放促进剂和用于治疗由小脑中的GABA缺乏引起的病理学症状的组合物,每种包含Best1通道激活剂作为活性成分; 并提供了使用Best1通道作为靶标筛选小脑中的GABA释放调节剂的方法。
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