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1.发明申请公开(公告)号：US20090271119A1
公开(公告)日：2009-10-29
申请号：US12083094
申请日：2006-08-22
CPC分类号： A61M1/28 , A61M1/1613
摘要： It is intended to provide a method whereby the peritoneal function of a dialysis patient can be tested by a relatively easy procedure and yet a high accuracy can be achieved compared with the existing methods, and an apparatus for the peritoneal function test by using the same. Standards of four kinetic parameters (CCr, Kt/V, MTACu, and MTACc) available in a definite dialysis guideline are computed in accordance with the relational expression (formula (7)). The curve showing the relation between MTACu/c thus obtained and the drained fluid volume is indicated in a graph together with the PET data of the patient which has been prepared separately. Thus, the peritoneal function can be evaluated based on the relative position of the patient's data and the curve showing the standard values in the graph.
摘要翻译： 旨在提供一种可以通过相对容易的过程来测试透析患者的腹膜功能的方法，并且与现有方法相比可以实现高精度，以及通过使用该方法进行腹膜功能测试的装置。 根据关系式（公式（7））计算确定透析指南中可用的四种动力学参数（CCr，Kt / V，MTACu和MTACc）的标准。 显示如此获得的MTACu / c与排出的流体体积之间的关系的曲线与单独制备的患者的PET数据一起表示。 因此，可以基于患者数据的相对位置和示出图中的标准值的曲线来评估腹膜功能。
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2.发明授权公开(公告)号：US08303532B2
公开(公告)日：2012-11-06
申请号：US12083094
申请日：2006-08-22
IPC分类号： A61M1/00
CPC分类号： A61M1/28 , A61M1/1613
摘要： A peritoneal function testing apparatus tests the peritoneal function of a dialysis patient easily and with high accuracy. Standards of four kinetic parameters (CCr, Kt/V, MTACu, and MTACc) available in a definite dialysis guideline are computed in accordance with a relational expression, and a curve showing the relation between MTACu/c and the drained fluid volume is indicated in a graph together with the PET data of the patient which has been prepared separately. Thus, the peritoneal function can be evaluated based on the relative position of the patient's data and the curve showing the standard values in the graph.
摘要翻译： 腹膜功能测试仪容易且高精度地测试透析患者的腹膜功能。 根据关系表达式计算确定透析指南中可用的四种动力学参数（CCr，Kt / V，MTACu和MTACc）的标准，显示MTACu / c与排出的液体体积之间的关系的曲线表示在 与已经分开制备的患者的PET数据一起图。 因此，可以基于患者数据的相对位置和示出图中的标准值的曲线来评估腹膜功能。
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3.发明申请D/P CREATININE MARKER, METHOD OF DETERMINING D/P CREATININE, AND INTENDED USE THEREOF 审中-公开D / P CREATININE MARKER，确定D / P CREATININE的方法及其预期用途公开(公告)号：US20090208998A1
公开(公告)日：2009-08-20
申请号：US12305303
申请日：2007-09-26
申请人： Satoshi Hirai , Tomokazu Karino
发明人： Satoshi Hirai , Tomokazu Karino
IPC分类号： C07K14/435 , C12Q1/02
CPC分类号： G01N33/70 , G01N2333/76
摘要： A method of indirectly determining D/P creatinine for easily judging a peritoneal function is provided that does not require blood sampling or multiple recoveries of dialysis effluent. The method includes preparing a dialysis effluent obtained by peritoneal dialysis, measuring at least one protein marker selected from the group consisting of prealbumin, haptoglobin, alpha 1-microglobulin, C4, and total protein that are contained in the dialysis effluent, and determining D/P creatinine indirectly from the correlation equation that represents the relationship between the marker concentration and the D/P creatinine value that has been prepared beforehand. Furthermore, the PET category is determined indirectly from the D/P creatinine, which has been determined indirectly, based on the known reference value.
摘要翻译： 提供间接测定D / P肌酐以容易判断腹膜功能的方法，其不需要血液取样或多次回收透析流出物。 该方法包括制备通过腹膜透析获得的透析流出物，测量至少一种选自透析流出液中含有的前白蛋白，触珠蛋白，α1-微球蛋白，C4和总蛋白质的蛋白质标记，并测定D / P肌酸酐间接地代表了事先准备的标记浓度与D / P肌酐值之间关系的相关方程。 此外，PET类别是根据已知参考值间接确定的D / P肌酸酐间接确定的。
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