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    CARBON NANOTUBE BIOSENSORS WITH APTAMERS AS MOLECULAR RECOGNITION ELEMENTS AND METHOD FOR SENSING TARGET MATERIAL USING THE SAME
    1.
    发明申请
    CARBON NANOTUBE BIOSENSORS WITH APTAMERS AS MOLECULAR RECOGNITION ELEMENTS AND METHOD FOR SENSING TARGET MATERIAL USING THE SAME 有权
    具有APTAMERS的碳纳米管生物传感器作为分子识别元件和使用它们感测目标材料的方法

    公开(公告)号：US20080094078A1

    公开(公告)日：2008-04-24

    申请号：US11952310

    申请日：2007-12-07

    申请人： Hye So ,  Jeong Lee ,  Yong Kim ,  Ki Won ,  Hyun Chang ,  Beyong Ryu ,  Ki Kong ,  Young Choi

    发明人： Hye So ,  Jeong Lee ,  Yong Kim ,  Ki Won ,  Hyun Chang ,  Beyong Ryu ,  Ki Kong ,  Young Choi

    IPC分类号： G01R27/08 ,  H01L29/78 ,  C12Q1/68

    CPC分类号： G01N33/5308 ,  B82Y10/00 ,  B82Y30/00 ,  G01N27/4145 ,  G01N27/4146 ,  G01N33/551

    摘要： The present invention relates to a carbon nanotube transistor biosensor with aptamers and a method for detecting a target material using the same, more particularly to a carbon nanotube transistor biosensor recognizing the target material, i.e., a specific molecule (such as a protein, a peptide, an amino acid, and an organic/inorganic compound) by using DNA aptamers and a method for screening a target material using the same. In the biosensor of the present invention, the aptamers binding specifically to a particular protein are adsorbed on a carbon nanotube constituting the channel domain of carbon nanotube transistor to easily detect/identify a particular protein via the electric conductivity of carbon nanotube that varies if the particular protein is exposed to corresponding aptamers.

    摘要翻译： 本发明涉及具有适体的碳纳米管晶体管生物传感器和使用其的靶材料的检测方法，更具体地说，涉及识别靶材料的碳纳米管晶体管生物传感器，即特定分子（例如蛋白质，肽 ，氨基酸和有机/无机化合物）和使用其的筛选靶材的方法。 在本发明的生物传感器中，特异性结合特定蛋白质的适体被吸附在构成碳纳米管晶体管的沟道区域的碳纳米管上，以容易地通过碳纳米管的电导率来检测/识别特定的蛋白质， 蛋白质暴露于相应的适体。