公开(公告)号：US20190211370A1

公开(公告)日：2019-07-11

申请号：US16241680

申请日：2019-01-07

Applicant: IMPETUX OPTICS, S.L.

Inventor： Arnau FARRÉ FLAQUER ,  Ferran MARSÀ SAMPER

IPC: C12Q1/02 ,  G01N21/71 ,  G01N25/48

CPC classification number: C12Q1/02 ,  G01N21/718 ,  G01N25/482 ,  G01N33/48728 ,  G01N2201/06106 ,  G02B21/32

Abstract: A method to label as defective a measure of an optical-trap force, that is exerted on a trapped particle located inside a living, dispersive, viscoelastic medium, including operations of: (i) determining a calibration constant between the optical trap forces and the sensed voltages; (ii) determining a first calibration function of the frequency of the particle oscillation with the active-passive procedure; (iii) computing a second calibration function of the frequency as the quotient between the calibration constant and the first calibration function; (iv) computing an energy function of the frequency as the product of the thermal energy of the trapped particle and the second calibration function; (v) checking whether the energy function converges to the thermal energy of the trapped particle as the frequency increases; (vi) if there is no such convergence, then label as defective the measure of the optical-trap force.