公开(公告)号：US10556941B2

公开(公告)日：2020-02-11

申请号：US16156521

申请日：2018-10-10

申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE ,  UNIVERSITÉ DE BORDEAUX ,  UNIVERSITÉ DE RENNES ,  ECOLE DES HAUTES ETUDES EN SANTÉ PUBLIQUE (EHESP) ,  UNIVERSITÉ DES ANTILLES ET DE LA GUYANE ,  INSTITUT BERGONIÉ ,  UNIVERSITY OF NOTTINGHAM

发明人： Patrick Legembre ,  Pierre Vacher ,  Doriane Sanseau ,  Aubin Penna ,  Robin Flynn

IPC分类号： C07K14/70 ,  A61K38/00 ,  C07K14/705 ,  C07K14/525 ,  C07K16/00 ,  G01N33/68

摘要： The present invention relates to polypeptides and uses thereof for reducing CD95-meditated cell motility. In particular, the present invention relates to a polypeptide having an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino-acid residue at position 175 to the amino-acid residue at position 191 in SEQ ID NO:1.

公开(公告)号：US10189887B2

公开(公告)日：2019-01-29

申请号：US15304550

申请日：2015-04-16

申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) ,  UNIVERSITÉ DE BORDEAUX ,  UNIVERSITÉ DE RENNES ,  ECOLE DES HAUTES ETUDES EN SANTÉ PUBLIQUE (EHESP) ,  UNIVERSITÉ DES ANTILLES ET DE LA GUYANE ,  INSTITUT BERGONIÉ ,  UNIVERSITY OF NOTTINGHAM

发明人： Patrick Legembre ,  Pierre Vacher ,  Doriane Sanseau ,  Aubin Penna ,  Robin Flynn

IPC分类号： C07K14/70 ,  C07K16/00 ,  C07K14/705 ,  C07K14/525 ,  G01N33/68 ,  A61K38/00

摘要： The present invention relates to polypeptides and uses thereof for reducing CD95-meditated cell motility. In particular, the present invention relates to a polypeptide having an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino-acid residue at position 175 to the amino-acid residue at position 191 in SEQ ID NO:1.