专利检索 ap:("INSTITUT CURIE" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -" OR "HONING BIOSCIENCES") AND inv:"Zélia GOUVEIA" 第 1 页

1.

发明公开
HER2 SINGLE DOMAIN ANTIBODIES VARIANTS AND CARS THEREOF 审中-公开

公开(公告)号：US20240317890A1

公开(公告)日：2024-09-26

申请号：US18269615

申请日：2022-01-14

申请人： INSTITUT CURIE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS - , HONING BIOSCIENCES

发明人： Franck PEREZ , Sandrine MOUTEL , Zélia GOUVEIA

IPC分类号： C07K16/32 , A61K39/00 , C07K14/705 , C07K14/725 , G01N33/574

CPC分类号： C07K16/32 , C07K14/7051 , C07K14/70578 , G01N33/57484 , A61K2039/505 , C07K2317/24 , C07K2317/569 , C07K2317/73 , C07K2317/92 , C07K2319/03

摘要： The present invention relates to humanized HER2 single domain antibodies and variants thereof and their use in therapy and for cancer diagnosis. The invention most particularly proposes chimeric antigen receptors including said humanized HER2 sdAb in their antigen binding domain and their use in cancer cell therapy.