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公开(公告)号：US20190134293A1
公开(公告)日：2019-05-09
申请号：US16099621
申请日：2017-05-09
CPC分类号： A61M1/3618 , A61M1/0281 , A61M1/029 , A61M2202/0427 , B01D21/00 , B01D21/0009 , B03C1/01 , B03C2201/18 , B03C2201/26
摘要： Provided is an accelerated method for preparing platelet rich plasma (PrP) without centrifugation or filtration. The method comprises contacting a sample of whole blood with an anti-coagulant and an inducer of Rouleaux formation; allowing the mixture to stand thereby depleting the sample of RBCs, and collecting the platelet-rich plasma fraction. The PrP volume obtained by the present method is about 10-60% of the volume of the starting whole blood sample, and contains less than 200,000 RBCs and at least 100,000 platelets per microliter.
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公开(公告)号：US20090098204A1
公开(公告)日：2009-04-16
申请号：US12253372
申请日：2008-10-17
CPC分类号： A61L27/54 , A61K33/06 , A61K35/16 , A61K35/19 , A61K38/1858 , A61L27/10 , A61L2300/258 , A61L2300/414 , A61K2300/00
摘要： The invention provides biocompatible, biodegradable calcium sulfate matrices containing calcium sulfate activated platelets for use in tissue formation. The matrices are particularly useful in stimulating hard tissue, for example, bone formation. The matrices may also further include a growth factor and/or a transfectable gene, the inclusion of which may be useful in stimulating the growth of tissue of interest.
摘要翻译： 本发明提供生物相容的，可生物降解的硫酸钙基质，其含有用于组织形成的硫酸钙活化血小板。 该基质特别可用于刺激硬组织，例如骨形成。 所述基质还可以进一步包括生长因子和/或可转染基因，其包含可用于刺激感兴趣组织的生长。
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