公开(公告)号：US20140088036A1

公开(公告)日：2014-03-27

申请号：US13877094

申请日：2011-09-30

申请人： Jean Marie Lehn ,  Yves Claude Nicolau ,  Rajamalleswaramma Jogireddy ,  Adam H. Brockman ,  John Hey ,  Yongxin Yu

发明人： Jean Marie Lehn ,  Yves Claude Nicolau ,  Rajamalleswaramma Jogireddy ,  Adam H. Brockman ,  John Hey ,  Yongxin Yu

IPC分类号： C07H13/00 ,  C07H13/12 ,  A61K31/7024

CPC分类号： A61K31/7028 ,  A61K31/7024 ,  C07H11/04 ,  C07H13/00 ,  C07H13/12 ,  C07H15/04

摘要： The present invention provides, among other things, phosphorylated and pyrophosphate derivatives of mono-, di- and oligosaccharides, as well as structural derivatives of these compounds. These compounds have a variety of uses including for pharmaceutical applications. Also provided are methods of use in the treatment of disease, including diseases related to oxygen delivery.

公开(公告)号：US20140155334A1

公开(公告)日：2014-06-05

申请号：US14089380

申请日：2013-11-25

申请人： Jean-Marie Lehn ,  Yves Claude Nicolau ,  Rajamalleswaramma Jogireddy ,  Adam H. Brockman ,  John Hey ,  Yongxin Yu

发明人： Jean-Marie Lehn ,  Yves Claude Nicolau ,  Rajamalleswaramma Jogireddy ,  Adam H. Brockman ,  John Hey ,  Yongxin Yu

IPC分类号： A61K31/7028 ,  C07H11/04

CPC分类号： A61K31/7028 ,  A61K31/7024 ,  C07H11/04 ,  C07H13/00 ,  C07H13/12 ,  C07H15/04

摘要： The present invention provides, among other things, phosphorylated and pyrophosphate derivatives of mono-, di- and oligosaccharides, as well as structural derivatives of these compounds. These compounds have a variety of uses including for pharmaceutical applications. Also provided are methods of use in the treatment of disease, including diseases related to oxygen delivery.

摘要翻译： 本发明尤其提供单糖，二糖和寡糖的磷酸化和焦磷酸衍生物以及这些化合物的结构衍生物。 这些化合物具有多种用途，包括用于药物应用。 还提供了用于治疗疾病的方法，包括与氧气递送相关的疾病。