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公开(公告)号：US20090281087A1
公开(公告)日：2009-11-12
申请号：US12315831
申请日：2008-12-05
申请人： Joseph W. Boyd , Giles A. Brown , Michael Higginbottom , Viet-Anh Anne Horgan (nee Nguyen) , Jaqueline Ouzman , Iain Simpson
发明人： Joseph W. Boyd , Giles A. Brown , Michael Higginbottom , Viet-Anh Anne Horgan (nee Nguyen) , Jaqueline Ouzman , Iain Simpson
IPC分类号： A61K31/551 , C07D401/02 , A61K31/496 , C07D403/02 , C07D241/04 , C07D243/08 , A61P3/04 , A61P3/00 , A61P15/08 , A61P37/00 , A61P29/00 , A61P9/00
CPC分类号： C07D295/205
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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2.发明授权公开(公告)号：US08093248B2
公开(公告)日：2012-01-10
申请号：US12315831
申请日：2008-12-05
申请人： Joseph W. Boyd , Giles A. Brown , Michael Higginbottom , Viet-Anh Anne Horgan (Nee Nguyen) , Jaqueline Ouzman , Iain Simpson
发明人： Joseph W. Boyd , Giles A. Brown , Michael Higginbottom , Viet-Anh Anne Horgan (Nee Nguyen) , Jaqueline Ouzman , Iain Simpson
IPC分类号： C07D295/185 , C07D401/12 , A61K31/496
CPC分类号： C07D295/205
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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公开(公告)号：US20110046135A1
公开(公告)日：2011-02-24
申请号：US12917085
申请日：2010-11-01
IPC分类号： A61K31/5355 , C07D401/12 , C07D241/14 , C07D413/12 , A61K31/497 , A61P17/02 , A61P9/10 , A61P9/00 , A61P37/00
CPC分类号： C07D211/22 , C07D241/04 , C07D265/30
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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公开(公告)号：US20110059969A1
公开(公告)日：2011-03-10
申请号：US12744359
申请日：2008-12-05
IPC分类号： A61K31/5377 , C07D401/12 , A61K31/496 , C07D403/12 , C07D413/12 , A61P3/04 , A61P3/00 , A61P9/12 , A61P17/00 , A61P15/08
CPC分类号： C07D211/22 , C07D241/04 , C07D265/30
摘要： The present invention relates to new compounds of formula (I), to pharmaceutical compositions comprising these compounds, to processes for their preparation, and to the use of these compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本发明涉及新的式（I）化合物，包含这些化合物的药物组合物，其制备方法以及这些化合物作为瘦素受体调节剂模拟物在制备抗体与体重增加相关的病症中的用途， 2型糖尿病和血脂异常。
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公开(公告)号：US07851471B2
公开(公告)日：2010-12-14
申请号：US12315698
申请日：2008-12-05
IPC分类号： A61K31/535 , A61K31/497 , C07D413/00 , C07D405/00 , C07D409/00 , C07D411/00
CPC分类号： C07D211/22 , C07D241/04 , C07D265/30
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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公开(公告)号：US20090181967A1
公开(公告)日：2009-07-16
申请号：US12315698
申请日：2008-12-05
IPC分类号： A61K31/5355 , C07D401/12 , C07D241/04 , C07D413/12 , A61K31/497 , A61P3/10
CPC分类号： C07D211/22 , C07D241/04 , C07D265/30
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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公开(公告)号：US20090176798A1
公开(公告)日：2009-07-09
申请号：US12315824
申请日：2008-12-05
IPC分类号： A61K31/496 , C07D401/12 , C07D403/12 , A61K31/4725 , A61P3/00 , A61P29/00 , A61P9/00
CPC分类号： C07D401/12 , C07D403/12
摘要： The present application relates to new compounds of formula (I), to pharmaceutical compositions comprising the compounds, to processes for their preparation, and to the use of the compounds as leptin receptor modulator mimetics in the preparation of medicaments against conditions associated with weight gain, type 2 diabetes and dyslipidemias.
摘要翻译： 本申请涉及新的式（I）化合物，包含该化合物的药物组合物，其制备方法，以及该化合物作为瘦蛋白受体调节剂模拟物在制备抗体与增重相关的病症中的用途， 2型糖尿病和血脂异常。
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