公开(公告)号：US20170056461A1

公开(公告)日：2017-03-02

申请号：US15242762

申请日：2016-08-22

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jae Wook LEE ,  Ju Young LEE ,  Jin Soo PARK ,  Jin Wook CHA ,  Hak Cheol KWON ,  Su-Nam KIM ,  Byung Hun UM

IPC: A61K36/28 ,  A23L33/105

CPC classification number: A61K36/28

Abstract: The present disclosure relates to a composition which comprises Centipede minima as an active ingredient. The composition of the present disclosure exhibits an effect of protecting neuronal cells from oxidative stress and inhibiting apoptosis of neuronal cells. In addition, the composition can increase expression of antioxidant enzymes which inhibit cellular apoptosis caused by increased oxidative stress in cells. Accordingly, the composition of the present disclosure can exhibit an effect of preventing, improving or treating secondary diseases that may be caused by apoptosis of neuronal cells due to oxidative stress and can be used as a pharmaceutical or food composition.

Abstract translation: 本公开涉及包含蜈蚣作为活性成分的组合物。 本公开的组合物显示出保护神经元细胞免受氧化应激和抑制神经元细胞凋亡的作用。 此外，该组合物可以增加抑制细胞中氧化应激增加引起的细胞凋亡的抗氧化酶的表达。 因此，本公开的组合物可以表现出预防，改善或治疗由于氧化应激可能由神经元细胞的凋亡引起的继发性疾病的作用，并且可以用作药物或食物组合物。