公开(公告)号：US09284550B2

公开(公告)日：2016-03-15

申请号：US14446651

申请日：2014-07-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byoung Chan Kim ,  Yeon Seok Kim ,  Jin Yang Chung ,  Jong Soo Jurng ,  Min Young Song

IPC: C07H21/02 ,  C07H21/04 ,  C12Q1/68 ,  G01N33/50 ,  C12N15/11 ,  G01N33/53 ,  G01N33/569 ,  C12N15/115

CPC classification number: C12N15/11 ,  C12N15/115 ,  C12N2310/16 ,  C12N2310/3181 ,  C12N2320/11 ,  G01N33/5308 ,  G01N33/56916 ,  G01N2333/26

Abstract: Provided is a single-stranded nucleic acid aptamer specifically binding to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae by using the same. The aptamer of the present disclosure, and a method, a composition, a kit or a sensor of using the same may be used to specifically detect Klebsiella pneumoniae present in an aqueous environment, foods, and medical samples and also be applied in fields such as sanitary conditions of foods and medical diagnosis.

Abstract translation: 本发明提供了特异性结合肺炎克雷伯氏杆菌的单链核酸适体和通过使用该克隆氏杆菌检测肺炎克雷伯氏杆菌的方法。 本公开的适体，以及使用其的方法，组合物，试剂盒或传感器可以用于特异性检测存在于水性环境，食品和医用样品中的肺炎克雷伯杆菌，并且也可以应用于例如 食品卫生条件和医疗诊断。

公开(公告)号：US09551709B2

公开(公告)日：2017-01-24

申请号：US14623082

申请日：2015-02-16

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byoung Chan Kim ,  Min Young Song ,  Jin Yang Chung ,  Jong Soo Jurng

IPC: C07H21/02 ,  G01N33/569 ,  C12N15/10 ,  G01N33/53

CPC classification number: G01N33/56938 ,  C12N15/1048 ,  G01N33/5308 ,  G01N33/56916 ,  G01N2333/245 ,  G01N2333/26 ,  G01N2333/265 ,  G01N2333/31 ,  G01N2333/32

Abstract: Provided are a single-stranded nucleic acid aptamer simultaneously and specifically binding to various types of microorganisms, and a method of manufacturing the nucleic acid aptamer. For example, provided are a probe that is capable of simultaneously detecting or diagnosing a variety of microorganisms, and a method of manufacturing an aptamer having characteristics of such a probe.

Abstract translation: 提供同时且特异性结合各种微生物的单链核酸适体，以及制备核酸适体的方法。 例如，提供能够同时检测或诊断各种微生物的探针，以及制造具有这种探针特征的适体的方法。