公开(公告)号：US09284550B2

公开(公告)日：2016-03-15

申请号：US14446651

申请日：2014-07-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byoung Chan Kim ,  Yeon Seok Kim ,  Jin Yang Chung ,  Jong Soo Jurng ,  Min Young Song

IPC: C07H21/02 ,  C07H21/04 ,  C12Q1/68 ,  G01N33/50 ,  C12N15/11 ,  G01N33/53 ,  G01N33/569 ,  C12N15/115

CPC classification number: C12N15/11 ,  C12N15/115 ,  C12N2310/16 ,  C12N2310/3181 ,  C12N2320/11 ,  G01N33/5308 ,  G01N33/56916 ,  G01N2333/26

Abstract: Provided is a single-stranded nucleic acid aptamer specifically binding to Klebsiella pneumoniae, and a method for detecting Klebsiella pneumoniae by using the same. The aptamer of the present disclosure, and a method, a composition, a kit or a sensor of using the same may be used to specifically detect Klebsiella pneumoniae present in an aqueous environment, foods, and medical samples and also be applied in fields such as sanitary conditions of foods and medical diagnosis.

Abstract translation: 本发明提供了特异性结合肺炎克雷伯氏杆菌的单链核酸适体和通过使用该克隆氏杆菌检测肺炎克雷伯氏杆菌的方法。 本公开的适体，以及使用其的方法，组合物，试剂盒或传感器可以用于特异性检测存在于水性环境，食品和医用样品中的肺炎克雷伯杆菌，并且也可以应用于例如 食品卫生条件和医疗诊断。

公开(公告)号：US09034254B2

公开(公告)日：2015-05-19

申请号：US13672399

申请日：2012-11-08

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byoung Chan Kim ,  Jong Soo Jurng ,  Min Young Song

IPC: A61L2/00 ,  C09K3/00 ,  A61L9/00 ,  G01N33/53 ,  A61L2/10 ,  A61L2/08

CPC classification number: A61L2/10 ,  A61L2/088

Abstract: Disclosed is an antibacterial composition comprising titanium oxide particles immobilized with an antibody having affinity and cognitive power to a microorganism of interest, and a method for sterilizing the microorganism by using the same. In particular, the present invention relates to a method for preparing functional titanium oxide particles capable of recognizing a microorganism or a virus of interest, and a method for selectively and efficiently sterilizing the same by using the functional titanium oxide particles, and not for randomly sterilizing microorganisms or viruses by using conventional titanium oxide particles having no recognition power to a microorganism or a virus of interest.

Abstract translation: 公开了一种抗菌组合物，其包含固定有对感兴趣的微生物具有亲和力和认知能力的抗体的氧化钛颗粒，以及使用该微生物的方法。 特别地，本发明涉及一种能够识别感兴趣的微生物或感兴趣的病毒的功能性氧化钛粒子的方法，以及通过使用所述功能性氧化钛粒子选择性且有效地对其消毒的方法，而不是用于随机灭菌 通过使用对感兴趣的微生物或感兴趣的病毒不具有识别能力的常规氧化钛颗粒的微生物或病毒。

公开(公告)号：US09551709B2

公开(公告)日：2017-01-24

申请号：US14623082

申请日：2015-02-16

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Byoung Chan Kim ,  Min Young Song ,  Jin Yang Chung ,  Jong Soo Jurng

IPC: C07H21/02 ,  G01N33/569 ,  C12N15/10 ,  G01N33/53

CPC classification number: G01N33/56938 ,  C12N15/1048 ,  G01N33/5308 ,  G01N33/56916 ,  G01N2333/245 ,  G01N2333/26 ,  G01N2333/265 ,  G01N2333/31 ,  G01N2333/32

Abstract: Provided are a single-stranded nucleic acid aptamer simultaneously and specifically binding to various types of microorganisms, and a method of manufacturing the nucleic acid aptamer. For example, provided are a probe that is capable of simultaneously detecting or diagnosing a variety of microorganisms, and a method of manufacturing an aptamer having characteristics of such a probe.

Abstract translation: 提供同时且特异性结合各种微生物的单链核酸适体，以及制备核酸适体的方法。 例如，提供能够同时检测或诊断各种微生物的探针，以及制造具有这种探针特征的适体的方法。